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Radiation Protection

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Question
Answer
Radiobiology   show
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Adverse effects of ionizing radiation effect?   show
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What are the attributes of ionizing radiations?   show
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What is used to Determine the extent different radiation modalities transfer energy into biologic tissues?   show
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show The average energy deposited per unit path length of “track” as it traverses a material medium.  
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What is an important factor in assessing potential tissue and organ damage from ionizing radiation?   show
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x & gamma radiation, no charge, Sparsely ionizing and interacts randomly along it’s trak, & cause damage through Indirect Action is know as what type of LET?   show
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Ionizing radiation with mass and charge, Densely Ionizing along track, Alpha Particles, Heavy Nuclei Ions, Charged Particles, Neutrons are know as what type of LET?   show
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What is the formula for Linear Energy Transfer (LET)?   show
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What is the size of DNA?   show
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Electron vs. Alpha   show
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Relative Biological Effectiveness (RBE)   show
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what is the formula for RBE?   show
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show Many chemicals can change the response of cells to radiation. the one that has a very big effect and is important in Radiobiology is oxygen.  
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show oxygen  
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show Oxygen is most effective when administered simultaneously with the radiation.  
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show OER= Hypoxic/ Oxygenated  
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Effects of Ionizing Radiation where observed in what 3 levels?   show
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Any induced injuries on living systems by radiation is a consequence of damage at what level?   show
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Direct Action   show
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Indirect Action   show
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How are free radicals produced?   show
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show Free Radicals  
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Single Strand Breaks   show
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show Single Strand Breaks  
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Double Strand Break   show
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What break is common with High LET radiation & damage to Nitrogenous bases?   show
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show High LET  
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show Metaphase and Anaphase  
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What is the irreplaceable master molecule in cell?   show
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show 1000Gy received secs to mins will disrupt the cell and cause death.  
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show 1- 10Gy Cells does not die , but loses reproductive abilities  
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Apoptosis   show
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Mitotic Death   show
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show 0.01 Gy at beginning of division can cause mitotic delay No known cause.  
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show Cell irradiation during mitosis can lead to chromosomal breakage.  
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show Relates sensitivity of a particular type of cell to ionizing radiation.  
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show Radiation has a more damaging effect on cells that are: -Rapidly dividing -Have Long Mitotic Cycle -Immature stage in development Undifferentiated cells  
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Most Sensitive   show
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Least sensitive   show
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show Established that Radiosensitivity is a function of the metabolic state of cell while irradiating Germ cell studies  
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Radiosensitivity   show
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Hematologic Depression   show
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Immature Blood Cells   show
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show BM cells can repopulate if low dose received  
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show stems cells  
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What is the Lethal Dose of radiation in animals?   show
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show LD 50/60 *3-4 Gy  
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show *“Scavenger” WBC *Increase in number in response to irradiation *Then decrease rapidly, then decrease slowly  
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show *Blood clotting and prevent Hemorrhaging *Lifespan of 30 days *50 rads (0.5Gy)  
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Cell Survival Curves   show
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show *Implanted *Ingested *Injected *Inhaled  
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show 1. Chromosomal aberrations 2. Chromatid aberrations  
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