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Paramedic Pharmocology & Skills

Quiz yourself by thinking what should be in each of the black spaces below before clicking on it to display the answer.
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Question
Answer
Sodium Bicarb chemical name   NaHCO3  
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Sodium Bicarb indications   Late in management of cardiac arrest (if at all), severe acidosis refractory to hyperventilation,hyperkalemia, upon return of spontaneous circulation after long arrest interval, tricyclic antidepressant overdose, phenobarbital overdose.  
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Sodium Bicarb contraindications   In patients with chloride loss from vomiting and GI suction, Metabolic and respiratory alkalosis, Hypocalcemia, Hypokalemia  
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Sodium Bicarb side effects   Metabolic alkalosis, fluid overload, tissue necrosis if extravasation occurs.  
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Sodium Bicarb adult dose   1 mEq/kg, repeat with 0.5 mEq/kg every 10 minutes  
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Sodium Bicarb pediatric dose   1 mEq/kg, repeat with 0.5 mEq/kg every 10 minutes (infuse slowly)  
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Sodium Bicarb class   buffer  
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Norepinephrine trade names   Levophed, Levarterenol  
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Norepinephrine indications   cardiogenic shock, significant hypotension (>70mm Hg)  
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Norepinephrine contraindications   Hypotension with hypovolemia, pregnancy  
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Norepinephrine class   Sympathomimetic  
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Norepinephrine adult dose   Dilute 8 mg in 500 mL of D5W or 4 mg in 250 mL of D5W (16ug/mL); infuse by IV piggyback at 0.5-1.0 ug/min, titrated to improve blood pressure (up to 30ug/min)  
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Norepinephrine pediatric dose   0.1-1.0 ug/ming IV insfusion, titrated to patient response  
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Norepinephrine side effects   Headache, arrhythmias, tachycardia, reflex bradycardia, angina pectoris, HTN, decreased perfusion to GI, kidney, skeletal muscle, and skin  
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Albuterol Class   Sypathomimetic, bronchodilator  
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Albuterol trade names   Proventil, Ventolin  
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Albuterol indications   bronchospasm in patients with reversible obstructive airway disease (COPD/Ashtma). Prevention of exercise induced bronchospasm.  
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Albuterol contraindications   Known prior hypersensitivity reactions to albuterol. Tachycardia arrhythmias, especially those caused by digitalis. Synergistic with other sympathomimetics.  
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Albuterol side effects   Often dose related including: restlessness, tremors, dizziness, palpitations, tachycardia, nervousness, peripheral vasodilation, nausea, vomiting, hyperglycemia, increased blood pressure, and paradoxical bronchospam  
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Albuterol Adult dose for Nebulizer   2.5 mg. Dilute 0.5 mL or 0.5% solution for inhalation with 2.5 mL normal saline in nebulizer and administer over 10-15 minutes.  
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Albuterol Adult dose for MDI   1-2 inhalations (90-180 ug). Five minutes between inhalations.  
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Albuterol Pediatric dose for Nebulizer   solution of 0.01-0.03 mL (0.05-0.15 mg/kg/dose diluted in 2 mL of 0.9% normal saline. May repeat every 20 minutes 3 times.  
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Oxygen class   Naturally occuring gas. DUH.  
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Oxygen indications   Confirmed or suspected hypoxemia, ischemic chest pain, respitory insufficiency, prophylactically during air transport, confirmed or suspected carbon monoxide poisoning, all other causes of decreased tissue deoxygenation, deceased level of consciousness.  
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Oxygen contraindications   Certain patients with COPD or emphysema who will not tolerate oxygen concentrations over 35%, hyperventilation.  
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Oxygen adult/pedi dose   Cardiac arrest and carbon monoxide poisoning: 100%. Hypoxemia 10-15 L/min via NRB. COPD 1-6 L/min via NC or 28%-35% VM. EXCEPTION: Premature infant, no more than 30-40% oxygen  
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Oxygen side effects   Decreased level of consciousness and respitory depression in patients with chronic carbon dioxide retention. Retrolental fibroplasia if high concentrations are given to premature infants.  
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OPA indications   Unresponsive patients, absent gag reflex  
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OPA contraindications   Conscious patients, patients WITH gag reflex  
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OPA advantages   Noninvasive, easily placed, prevents blockage of the glottis by the tongue  
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OPA disadvantages   Does not prevent aspiration  
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NPA indications   Unresponsive patients, patients with AMS who have a gag reflex  
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NPA contraindications   Patient intolerance, most facial fractures or skull fractures  
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NPA advantages   Can be suctioned through, provides a patent airway, can be tolerated by conscious patients, may be placed blindly, does not require use of the oropharynx  
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NPA disadvantages   May result in excessive bleeding, does not protect from aspiration.  
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BVM indications   patients in respitory failure  
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BVM contraindications   patients who are breathing adequately, patients who cannot tolerate the device  
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BVM advantages   Delivers 100% O2 to the patient, allows extended ventilation time without rescuer fatigue, provides excellent barrier from body fluids  
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BVM disadvantages   Difficult to maintain proper seal, requires great effort to master technique, can result in inadequate tidal volume if rescuer is inexperienced with device  
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Epinephrine class   Sympathomimetic  
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Epi-Cardiac arrest indications   Cardiac Arrest (V-fib/pulseless V-tach, asystole, PEA)  
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Epi-Cardiac related indications   Symptomatic bradycardia as an alternative to dopamine infusion. For severe hypotension secondary to bradycardia when atropine and subcutaneous pacing are unsuccessful.  
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Epi-Non-Cardiac related indications   Allergic Reactions, Anaphalaxis, Ashtma  
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Epi-Contraindications   HTN, hypothermia, pulmonary edema, myocardial ischemia, hypovolemic shock  
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Epi-Side effects   HTN, tachycardia, angina, arrythmias, pulmonary edema, psychomotor agitation, headache, nausea, anxiety, restlessness  
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Epi-Adult dose for mild allergic reactions and Asthma   0.3-0.5 mg  
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Epi-Pediatric dose for mild allergic reactions and asthma   0.1 mg/kg up to 0.3 mg  
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Epi-Adult dose for Anaphalaxis   0.1 mg (1ml of 1:10000) IV/IO over 5 minutes  
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Epi-Adult dose for Cardiac arrest   IV/IO dose: 1 mg (10 mL of 1:10,000 solution) every 3-5 minutes during resuscitation. Follow each dose with 20 mL flush and elevate arm for 10-20 seconds after dose. Higher dose for beta blocker or calcium channel blocker overdose: up to .2mg/kg  
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Epi-Pediatric dose for cardiac arrest   0.01 mg/kg (0.1 mL/kg) of 1:10,000 solution every 3-5 minutes during arrest.  
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Epi-Adult dose for Cardiac arrest with ET tube   2-2.5 mg diluted in 10 mL normal saline.  
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Epi-Pediatric dose for cardiac arrest with ET tube   0.1 mg/kg (0.1 mL/kg) or 1:1,000 solution.  
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Epi-Adult dose for profound bradycardia or hypotension   2-10 ug/min titrate to patient response.  
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Epi-Pediatric dose for symptomatic bradycardia   0.1 mg/kg (0.1 mL/kg) of 1:10,000 solution  
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Epi-Adult dose for continuous infusion   Add 1 mg (1 mL of 1:1,000 solution) to 500 mL normal saline or D5W. Initial infusion rate or 1 ug/min titrated to effect (typical dose:2-10 ug/min)  
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Epi-Pediatric dose for continuous infusion   begin with rapid infusion, then titrate to response. Typical initial infusion: 0.1-1 ug/min. Higher doses may be effective.  
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Atropine Sulfate Class   Anticholinergic Agent  
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Atropine Sulfate Indications   Hemodynamically unstable bradycardia, bradycardic PEA, asystole, bronchospastic pulmonary disorders, organophosphate poisoning  
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Atropine Sulfate Contraindications   Tachycardia, unstable cardiovascular status in acute hemorrhage and myocardial ischemia, hypersensitivity, narrow-angle glaucoma, Pregnancy Category C  
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Atropine Sulfate Side Effects   Tachycardia, arrythmias, palpitations, paradoxical bradycardia when pushed slowly or in low doses, headache, dizziness, flushed/hot/dry skin, blurred vision, dry mouth, urinary retention  
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Atropine Sulfate Adult Dose for Asystole or Bradycardic PEA   1 mg IV/IO push. May repeat every 3-5 minutes up to 3 mg.  
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Atropine Sulfate Pedi Dose   0.02 mg/kg via IV/IO ush, may double for second dose. Minimum Dose is 0.1 mg, maximum dose is 0.5 mg up to 1.0 mg / adolescent 1.0 mg up to 2.0 mg  
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Atropine Sulfate Adult ET Dose for Asystole or Bradycardic PEA   2.3 mg diluted in 10 ml of water or normal saline.  
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Atropine Sulfate Pedi ET Dose   0.03 mg/kg (absorption may be unreliable)  
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Atropine Sulfate Adult Dose for Unstable Bradycardia   0.5 mg IV/IO every 3-5 minutes, not to exceed 3.0 mg. In severe cases, shorter time interval of 3 minutes and higher dosage may help.  
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Atropine Sulfate Adult Dose for Organophosphate poisoning   2-4 mg or higher may be needed  
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Methylprednisolone Class   Anti-Inflammatory glucocorticoid  
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Methylprednisolone Trade Name   Solu-Medrol  
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Methylprednisolone Indications   Acute spinal cord trauma, anaphylaxis, bronchodilator for unresponsive asthma  
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Methylprednisolone Contraindications   Premature infants, systemic fungal infections, caution for GI bleeds  
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Methylprednisolone Side Effects   Sodium and Water retention, HTN, CHF, Headache, Nausea and Vomiting, Hypokalemia, Alkalosis, Peptic Ulcer Disease  
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Methylprednisolone Adult Dose for Acute Spinal Cord Trauma   30mg/kg IV over 30 minutes followed by infusion @ 5.4mg/kg/h  
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Methylprednisolone Pedi Dose for Acute Spinal Cord Trauma   30mg/kg IV over 30 minutes followed by infusion @ 5.4mg/kg/h  
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Methylprednisolone Adult Dose for Asthma & COPD   1-2mg/kg IV  
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Methylprednisolone Pedi Dose for Asthma   1-2 mg/kg/dose IV  
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Dopamine Class   Sympathomimetic, Inotropic Agent  
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Dopamine Trade Name   Intropin  
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Dopamine Indications   Cardiogenic/Septic/Spinal/Distributive Shock, Hypotension with Low Cardiac Output  
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Dopamine Contraindications   Hypovolemic Shock, Tachyarrythmias, V-Fib, Pheochromocytoma  
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Dopamine Side Effects   HTN, Arrhythmias, Increased Cardiac Oxygen Demand, Tissue Necrosis if Extravated  
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Dopamine Adult Dose   2-20ug/kg/min tirtrated to patient response  
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Dopamine Pedi Dose   2-20 ug/kg/min titrated to patient response  
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Dobutamine Class   Sympathomimetic, Inotropic Agent  
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Dobutamine Trade Name   Dobutrex  
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Dobutamine Indications   CHF, Left Ventricular Dysfuntion, Cardiogenic Shock  
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Dobutamine Contraindications   Tachyarrhythmias, IHSS, Severe Hypotension, Incompatable with Sodium Bicarbonate and Furosemide  
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Dobutamine Side Effects   HTN, Headache, Arrythmias, PVC's, May increase Infart Size  
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Dobutamine Adult Dose   IV infusion at 2-20ug/kg/min titrated to desired effect  
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Dobutamine Pedi Dose   IV infusion at 2-20ug/kg/min titrated to desired effect  
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Diphenhydramine Class   Antihistamine, Anticholinergic  
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Diphenhydramine Trade Name   Benadryl  
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Diphenhydramine Indications   Allergic Reactions, Anaphylaxis, Actue Dystonic Reactions (Phenothiazines), Blood Administration Reactions, Motion Sickness, Hay Fever  
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Diphenhydramine Contraindications   HTN, Asthma, Glaucoma, Narrow Angle Glaucoma, MAOI Inhibitors, Pregnancy, Infants  
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Diphenhydramine Side Effects   Hypotension, Sedation, Seizures, Visual Disturbances, Urinary Retention, Vomiting, Arrythmias, Palpitations, Dry Mouth and Throat, Paradoxical CNS excitation in children  
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Diphenhydramine Adult Dose   25-50mg IM or IV or PO  
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Diphenhydramine Pedi Dose   1-2mg/kg IV, IO slowly or IM / PO 5mg/kg/24 hours  
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Midazolam Class   Short acting Benzodiazepine, CNS Depressant  
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Midazolam Trade Name   Versed  
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Midazolam Indications   Sedation, Anxiolytic prior to intubation, Conscious Sedation  
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Midazolam Contraindications   Shock, Depressed Vitals, Coma, Overdose, Glaucoma, Concomitant use with other CNS Depressants: Barbiturates, Alcohol, Narcotics, Not recommended in Pediatrics  
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Midazolam Adult Dose   2.0-2.5 mg IV slowly over 2-3 minutes, may be repeated to total maximum of 0.1 mg/kg.  
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Dilatiazem Hydrochloride Class   Calcium Channel Blocker  
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Dilatiazem Hydrochloride Trade Name   Cardizem, Lyo-Ject  
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Dilatiazem Hydrochloride Indications   Control of Rapid Ventricular Rates due to Atrial Flutter, Atrial Fib, And Re-Entry SVT; Angina Pectoris  
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Dilatiazem Hydrochloride Contraindications   Hypotesion, High Degree AV Blocks, Sick Sinus Syndrome, Wide-Complex Tachycardias, Poison/Drug Induced Tachycardia, Cardiogenic Shock  
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Dilatiazem Hydrochloride Side Effects   Bradycardia, High-Degree AV Blocks, Chest Pain, CHF, Syncope, V-Fib, V-Tach, Nausea, Vomiting, Dizziness, Dry Mouth, Dyspnea, Headache  
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Dilatiazem Hydrochloride Adult Dose   0.25mg/kg (about 15-20mg) IV over 2 Minutes. May wait 15 minutes and administer 0.35mg/kg (about 20-25mg) IV over 2 minutes. Maintenance Infusion of 5-15 mg/h. Not Recommended for Pediatrics.  
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Morphine Sulfate Class   Opiod Analgesic  
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Morphine Sulfate Trade Name   Astramorph/PF and many others  
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Morphine Sulfate Indications   Severe CHF, Pulmonary Edema, Chest Pain Associated with Actue MI, Analgesia for Moderate to Severe Acute and Chronic Pain (use with caution)  
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Morphine Sulfate Contraindications   Head Injury, Exacerbated COPD, Depressed Respiratory Drive, Hypotension, Undiagnosed Abdominal Pain, Decreased Level of Consciousness, Suspected Hypovolemia, MAOI use within the past 14 days  
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Morphine Sulfate Side Effects   Respiratory Depression, Hypotension, Decreased LOC, Nausea, Vomiting, Bradycardia, Tachycardia, Syncope, Facial Flushing, Euphoria :-), Bronchospasm, Dry Mouth  
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Morphine Sulfate Adult Dose   2-4mg IV over 1-5 minutes, every 5-30 minutes. May repeat dose at 2-8mg at 5-15 minute intervals  
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Morphine Sulfate Pedi Dose   0.1-0.2mg/kg via IV, IO, IM, or SC. Max dose of 5mg  
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Nitroglycerin Class   Vasodilator  
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Nitroglycerin Trade Name   Nitrostat, Tridil, and others  
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Nitroglycerin Indications   Actue Angina Pectoris, Ishcemic Chest Pain, Hypertension, CHF, Pulmonary Edema  
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Nitroglycerin Contraindications   Hypotension, Hypovolemia, Intracranial Bleeding or Head Injury, Phosphodiesterase Inhibitors (ex. Viagra) in the past 24 hours  
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Nitroglycerin Side Effects   Headache, Hypotension, Syncope, Reflex Tachycardia, Flushing, Nausea, Vomiting, Diaphoresis, Muscle Twitching  
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Nitroglycerin Adult Dose   0.3-0.4mg Tablets / 0.4mg Spay SL; May repeat every 3-5 minutes up to 3 doses (not recommended for use in pediatrics)  
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Adenosine Class   Endogenous Nucleotide  
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Adenosine Trade Name   Adenocard  
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Adenosine Indications   Conversion of PSVT to Sinus Rythym. May convert Re-Entry SVT due to Wolff-Parkinson-White Syndrome.  
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Adenosine Contraindications   Second or Third Degree Block or Sick Sinus Syndrome, A-Flutter, A-Fib, V-Tach, Hypersensitivy to Adenosine, Poison-Induced Tachycardia  
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Adenosine Side Effects   Facial Flushing, SOB, Chest Pain, Headache, Paresthesia, Diaphoresis, Palpitations, Hypotension, Nausea, Metallic Taste  
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Adenosine Adult Dose   6mg rapid IV push immediately followed by 20ml Saline Flush and Extremity Elevation. May Administer a Second and Third dose of 12mg in 1-2 Minute Intervals if no Initial Response  
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Adenosine Pedi Dose   0.1-0.2mg/kg rapid IV push, Maximum Single Dose of 12mg  
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Amiodarone Class   Antiarrhythmic  
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Amiodarone Trade Name   Cordaron, Pacerone  
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Amiodarone Indications   V-Fib, Pulseless V-Tach and Unstable V-Tach in Patients Refractory to Other Therapy  
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Amiodarone Contraindications   Known Hypersensitivity, Cardiogenic Shock, Sinus Bradycardia, Second or Third Degree Block in Absence of a Functioning Pacemaker  
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Amiodarone Side Effects   Hypotension, Bradycardia, Prolongation or the P-R, QRS, and Q-T Intervals  
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Amiodarone Adult Dose For V-Fib/Pulseless V-Tach   300mg IV Push, Repeated in 3-5 Minutes with 150mg IV Push  
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Amiodarone Adult Dose for Life Threatening and Recurring Ventricular Arrythmias   Rapid Infusion: 150 mg IV over 10 minutes. May Repeat Every Ten Minutes Slow Infusion: 360 mg over 6 Hours Maintenance Infusion: 540mg over 10 Hours Max Dose is 2.2g over 24 Hours  
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Amiodarone Pedi Dose for Refractory V-Fib/Pulseless V-Tach / Perfusing SVT/VT   5mg/kg IV Bolus (Over 20-60 Minutes for Perfusing SVT/VT) Max single dose is 300mg  
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Vasopressin Class   Antidiuretic Hormone  
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Vasopressin Trade Name   Pitressin Synthetic  
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Vasopressin Indications   Cardiac Arrest  
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Vasopressin Contraindications   Responsive Patients with CAD  
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Vasopressin Side Effects   Bronchoconstriction, Ischemic Chest Pain, Nausea and Vomiting, Abdominal Pain  
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Vasopressin Adult Dose   40 Units to Replace Either the First or Second Dose of Epinephrine during Cardiac Arrest. Not Recommended for Pediatrics.  
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Diltiazem Hydrochloride Class   Calcium Channel Blocker  
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Diltiazem Hydrochloride Trade Name   Cardizem, Lyo-Ject  
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Diltiazem Hydrochloride Indications   Control of Rapid Ventricular Rates Due to A-Flutter, A-Fib, and Re-Entry SVT; Angina Pectoris  
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Diltiazem Hydrochloride Contraindications   Hypotension, Sick Sinus Syndrome, Second or Third Degree Blocks, Cardiogenic Shock, Wide-Complex Tachycardias, Poison/Drug Induced Tachycardia  
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Diltiazem Hydrochloride Side Effects   Bradycardia, Second or Third Degree Blocks, Chest Pain, CHF, Syncope, V-Fib, V-Tach, Nausea, Vomiting, Dizziness, Dry Mouth, Dypsnea, Headache  
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Diltiazem Hydrochloride Adult Dose   0.25mg/kg IV over 2 minutes. May repeat in 15 minutes at 0.35mg/kg IV over 2 minutes. Maintainence Infusion of 5-15 mg/h. Not Recommended in Pediatrics  
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Glucagon Class   Hyperglycemic Agent, Pancreatic Hormone, Insulin Antagonist  
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Glucagon Trade Names   Glucagon  
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Glucagon Indications   Altered LOC when Hypoglycemia is suspected. May be uses as an Inotropic Agent in Beta-Blocker Overdose  
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Glucagon Contraindications   Hyperglycemia, Hypersensitivity  
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Glucagon Side Effects   Nausea, Vomiting, Tachycardia, Hypertension  
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Glucagon Adult Dose   Hypoglycemia: 0.5-1mg IM, May repeat in 7-10 Minutes Calcium Channel/Beta Blocker Overdose: 3mg , followed by infusion at 3mg/hr as necessary  
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Glucagon Pedi Dose   Hypoglycemia: 0.5-1mg IM for children less than 20kg. Not recommended for Calcium Channel/Beta Blocker Overdose in Pediatrics.  
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Oral Glucose Class   Hyperglycemic  
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Oral Glucose Trade Name   Insta-Glucose  
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Oral Glucose Indications   Concious Patients with suspected Hypoglycemia  
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Oral Glucose Contraindications   Decreased LOC, Nausea, Vomiting  
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Oral Glucose Side Effects   Nausea, Vomiting  
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Oral Glucose Dose   Should be Sipped Slowly Until Clinical Improvement Noted in Adults and Pediatrics  
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Thiamine Class   Vitamin B1  
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Thiamine Trade Name   Vitamin B1  
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Thiamine Indications   Coma of Unknown Origin, Delirium Tremens, Beribei, Wernicke's Encephalopathy  
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Thiamine Contraindications   None.  
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Thiamine Side Effects   Hypotension from Too Rapid of an Injection or Too High of a Dose, Anxiety, Diaphoresis, Nausea, Vomiting, Allergy  
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Thiamine Adult Dose   100mg Slow IV or IM  
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Thiamine Pediatric Dose   10-25 Slow IV or IM  
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Dextrose Class   Carbohydrate, Hypertonic Solution  
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Dextrose Trade Name   Dextrose  
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Dextrose Indications   Hypoglycemia, Altered LOC, Coma of Unknown Cause, Seizure of Unknown Cause, Status Epilepticus  
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Dextrose Contraindications   Intercranial Hemorrage  
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Dextrose Side Effects   Extraversion Leads to Tissue Necrosis. Warmth, Pain, Burning, Thrombophlebitis, Rhabdomyloysis, Hyperglycemia  
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Dextrose Adult Dose   12.5-25g Slow IV, repeat as Necessary  
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Dextrose Pedi Dose   0.5-1g/kg Slow IV, repeat as Necessary  
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Naloxone Hydrochloride Class   Narcotic Antagonist  
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Naloxone Hydrochloride Trade Name   Narcan  
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Naloxone Hydrochloride Indications   Opiate OD, Coma of Unknown Origin  
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Naloxone Hydrochloride Contraindications   Caution in Narcotic Dependant Patients, and Neonates of Narcotic Dependant Mothers  
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Naloxone Hydrochloride Side Effects   Withdrawal Symptoms in Addicted Patients, Tachycardia, Hypertension, Nausea and Vomiting, Diaphoresis  
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Naloxone Hydrochloride Adult Dose   0.4-2mg IV, IM, SC, or ET. Repeat in 5 Minutes to Max dose of 10mg. Infusion: 2mg in 500ml D5W at 0.4mg/hr  
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Naloxone Hydrochloride Pedi Dose   0.1mg/kg IV, IM, SC, or ET, Max dose of 0.8mg, repeat in 10 Minutes at 0.1mg/kg  
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