Final test Pharm UTA Fall 2010 (part 2)
Quiz yourself by thinking what should be in
each of the black spaces below before clicking
on it to display the answer.
Help!
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Side effects of Hematopoietic drugs | show 🗑
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show | Inmunomodulators
decrease progression of disease
Bone marrow suppression (SE * know)
Methotrexate
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show | Cause severe pain after second day
Given once a week
can depress bone marrow leading to
anemia
low WBCs
low platelets
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Hematopoietic drugs | show 🗑
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Positive inotropic agents | show 🗑
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show | B-blockers
ACE inhibitors
not congested state of HF
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show | Digoxin
Diuretics
Possitive inotropic drugs
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Digoxin mechanism of action | show 🗑
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uses of digoxin | show 🗑
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show | Narrow therapeutic index
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Digoxin drug interactions | show 🗑
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Digoxing formulations | show 🗑
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Digoxin IV | show 🗑
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Before giving Digoxin | show 🗑
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Major reason for Digoxin toxicity | show 🗑
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show | child= upset tummy
fatigue, headache, dizziness,anorexia, seizure if extreme
CARDIAC RHYTHM CHANGES
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show | Dilantin "phenotoin" DIGIBIND
Give K+
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show | if Heart Rate is below 60
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measurement of digoxin | show 🗑
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Therapeutic digoxin level | show 🗑
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show | clot that stays where is originated
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Embolus | show 🗑
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show | Inactivates thrombin preventing clot formation
It only prevents new clot formation and keep existing clots from growing
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when IV heparin is given | show 🗑
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show | Bolus dose no more than 50-100 units x kg BOLUS
between 1,500-2,500 units/hour INFUSION
20-30 units x min X KG
flushing lines 10-100 units
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Most severe side effect of heparin | show 🗑
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heparin and HIT | show 🗑
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Heparin drug interactions | show 🗑
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show | Protamine sulfate
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PTT Partial thromboplatin | show 🗑
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show | can be used by patients at home
inhibits factor Xa
less binding issues
PTT is not required
All doses are give subcutaneously
fewer problems than unfractionated
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Coumadin "Warfarin" | show 🗑
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show | DTV
A-fib "most common reason"
Clotting dissorders
Discontinued when PT/INR is in therapeutic range
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side effects of Warfarin | show 🗑
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show | glucocorticoids and aspirin increase bleeding Cold medications contain aspirin, Vit K " avoid on foods" Grape juice
Estrogens and barbiturates decrease effectiveness "increase metabolism"
BASs and antacids decrease absorption and level in the bod
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Antidote for Warfarin toxicity | show 🗑
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show | PTprothrombin time "time it takes to get activated"
INR international normalized ration universal standart of reporting pt results
Patients in warfarin should be on a 2-3 INR
Patients with liver failure will have an abnormal INR
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wear medic alert device | show 🗑
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antiplatelets | show 🗑
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show | patients with intracraneal pathology,
3-6 moths prior of GI bleeding or surgery
uncontrolled HTN
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show | Coagulation labs, PT/INR, PTT
CBCs look for anemia
Check CBCs often
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show | Herbs that start with letter G
Gingo
Garlic
Ginseng
Ginser
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PF4 antigen | show 🗑
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show | 60-80
if high stop or reduce drip
if low increase drip
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show | limit alcohol to 2 drinks x day
be consistand with vit K foods
atkin's/southbeach/green tea
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