Frusemide
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TYPE: | Loop diuretic
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PRESENTATION: | 80 mg in 8ml – IMS Mini-jet
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ACTIONS: | 1.Potent diuretic when given IV, Lasix increases urine output within 5 – 10 minutes; and can last up to 3 hours 2. Causes venous dilatation – decreases venous return. This effect occurs within 5 minutes.
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USE: | Severe Acute Cardiogenic Pulmonary Oedema – unresponsive to previous treatment – to decrease venous return and promote loss of fluid.
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ADVERSE EFFECTS | 1.If given too rapidly may lead to hypotension. 2.If marked diuresis,the resulting fluid loss may lead to hypovolaemic shock, especially in hypovolaemic patients 3. Potassium loss may occur – may aggravate arrhythmias (esp. if previously hypokalaemic
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CONTRA-INDICATIONS | 1. Systolic BP < 90mmHg 2. Hypersensitivity (Note – possible cross-sensitivity to sulphonamides)
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DOSE | Adult: On diuretics: 1 mg/kg IV over 2 minutes Adult Not on diuretics: 0.5 mg/kg IV over 2 minutes Single dose only
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Note | If the patient is in severe pulmonary oedema & IV access is not available, IM administration is acceptable. (use 2 separate sites if the volume is greater than 4mls) Paediatric: Not used
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