Ceftriaxone
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| Type | 3rd generation cephalosporin antibiotic
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| Presentation | Vial – 1g Ceftriaxone powder for reconstitution
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| Actions | 1. Broad spectrum antibiotic Especially effective against gram-negative bacteria(e.g. Meningococcus) 2. Effective crossing of blood-brain barrier
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| Use | Suspected meningococcal disease, in acutely ill patients
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| Adv Effects | 1. Hypersensitivity reactions (not common) 2. Diarrhoea 3. Skin rash
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| Precautions | It is possible that 20% patients with a Penicillin allergy may be sensitive to Ceftriaxone.
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| Contraindications | Known sensitivity to cephalosporins
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| Dose | 50 mg/kg, to 2g, IV preferred.also IO. Make to 10ml w/NS; give slowly over 2–4 min. May be administered IM:Dilute a maximum of 1g in 3mls of 1% Lignocaine prior to administration. Give two injections if dose is over 1g (i.e. over 3 mls volume
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| Special Note | An incident report should be submitted to Clinical Services if Ceftriaxone is administered.
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