chapter 17
Quiz yourself by thinking what should be in
each of the black spaces below before clicking
on it to display the answer.
Help!
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| Dna replication is initiated by? | show 🗑
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| M-CDK complex is activated by? | show 🗑
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| CKIs such as p27? | show 🗑
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| CDK activity is stimulated by phosphorylation of the T-loop by? | show 🗑
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| EdU incorporation marks cells in? | show 🗑
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| M cyclin levels fall when? | show 🗑
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| show | Flow cytometry
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| show | cyclin levels change during the cycle
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| What is true about CDC25 phosphatase? | show 🗑
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| show | Sister Chromatid
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| A key control system crucial for triggering cytokinesis is? | show 🗑
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| show | Cells produced would get smaller and smaller
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| show | Geminin
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| show | Wee1
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| show | inhibits PP2A-B55
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| show | keep PP2A-B55 active in early mitosis
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| Which mechanism serves as positive feedback to activate M-Cdks? | show 🗑
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| Cdt-1 is activated by? | show 🗑
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| show | chromosomes align at the spindle equator
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| show | compact chromosomes after being phosphorylated by M-CDK
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| Cdc-20-APC and Cdc-1-APC complexes are similar because? | show 🗑
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| ORC is phosphorylated in which phase? | show 🗑
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| DNA helices deposition on DNA at replication origins occurs mainly in which phase of cell cycle? | show 🗑
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| At the beginning of S phase in a cycling cell, what is likely to occur? | show 🗑
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| In the metaphase to anaphase transition, activation of which factor is important? | show 🗑
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| Which complex keeps M-cyclin levels low in G1 phase of cell cycle? | show 🗑
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| S-CDK ensures that replication happens only once per cycle by doing what? | show 🗑
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| show | Prometaphase
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| What is not true about APC? | show 🗑
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| show | Kinesin 5 on interpolar microtubules and dynein on astral microtubules
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| Which of these motor proteins are minus end directed motors that cross link inter polar microtubules and pull the poles together? | show 🗑
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| show | S phase
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| Polar ejection force that pulls chromosomes to the spindle equator is mediated by? | show 🗑
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| show | Pushes the chromosome arms away from the spindle poles with the help of kinesin 4 and 10
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| show | Yes!
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| show | astral microtubules
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| show | Kinetochore microtubules
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| Proper bi-orientation of the sister chromatid pair on the spindle generates a tension that is sensed by? | show 🗑
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| show | separation of sister chromatids
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| What is true about centrosomes? | show 🗑
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| Contractile ring is made of what? | show 🗑
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| show | must occur for kinetochore microtubules to form in animal cells
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| Do kinetochores assemble onto chromosomes during late prophase? | show 🗑
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| which event happens before the nuclear envelope is re-assembled in M phase? | show 🗑
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| Does taxol promote mitosis by stabilizing the spindle? | show 🗑
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| What are mitogens? | show 🗑
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| show | inhibition of cyclin-CDK complexes by p21
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| What would not occur as a result of genomic damage? | show 🗑
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| what contributes to helping cells progress from G1 to S phase? | show 🗑
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| show | Myc
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| show | Stabilizes p53
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| G1/S CDK also phosphorylates and inactivates APC/C towards the end of G1 phase, which directly helps in accumulation of? | show 🗑
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| show | High E2F activity
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| show | Cdc25
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| show | Chk-1
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| A regulator critical for enhancing cell growth through stimulation of protein synthesis rates is? | show 🗑
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