Pharm Emerg Med
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treatment priorities for sepsis | oxygen, aggressive fluid replacement, vasopressors (dopamine, dobutamine, norepi, vasopressin)
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empiric broad spectrum antibiotics used in sepsis | 3rd gen cephalosporins + aminoglycoside (ceftazidime and gentamycin), +/- vancomycin (MRSA)/clindamycin (anerobes)
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recombinant human activated protein C, only FDA approved drug used solely for the treatment of sepsis in the adult patient with high risk of death. only for use in the ICU | Xigris
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empiric treatment for bacterial meningitis | begin antibiotics immediately (ceftriaxone or cefotoaxime 2 g IV and vanc. add ampicillin for pts <3months/>55 and or immunocomp
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what do you add to empiric therapy for meningitis if HSV is suspected | acyclovir
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what do you give concurrently with empiric antibiotics when treating bacterial meningitis | dexamethasone, continue for 4 days
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supportive care for bacterial meningitis | hydration, pain meds, anticonv, antiemetics
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outpatient antibiotics for pneumonia | azithro, doxy, levo, cefpodoxime+azithro
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inpatient regimens for pneumonia | ceftriaxone+azithro, resp fluoroq, +/- vanc
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Duration of tx for uncomplicated cystitis in non-pregnant women/men | 3-5 days
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what is the duration of treatment for uncomplicated cystitis in children, preg women, and complicated infections in everyone else | 7-10 days
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antibiotics for cystitis | tmp/smz, nitrofurantoin, quinolones, cephalexin
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treatment for pyelonephritis | cipro 7-10 days, levo for 7 days, augmentin 10 days, cephalexin 10 days
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treatment of impetigo | cephalexin, diclox, mupirocin, retapamulin
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outpatient treatment for cellulitis | cephalexin, diclox, augmentin, doxy, minocycline, (MRSA-tmp/smx-bactrim or clinda
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inpatient treatment for cellulitis | IV clinda, IV vanc +/- cefazolin
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treatment of a fresh bite <24 hours old | exploration/irrigation/immobilization, primary closure if face/head/neck, tetanus/rabies prophylaxis
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prophylactic antibiotics for fresh bite | augmentin, moxifloxacin, clindamycin + ciprofloxacin
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incubation of malaria in returning travelers | varies from <2 weeks to >6 weeks
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PID tx | ceftriaxone + azithromycin OR doxycycline + metronidazole (outpatient)
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Chancroid tx | Ceftriaxone or zithro (1 dose)
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meningitis bugs: neonates | GBS, E coli, listeria; tx = amp & cefotaxime (Claforan)
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meningitis bugs: 1 mo - 50 yo | SP, Neisseria, H flu
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meningitis bugs: >50 yo / EtOH | SP, listeria; tx = amp + rocephin + dex
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meningitis tx: 1 - 3 mos | Amp + (rocephin or cefotaxime) + Dex
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meningitis tx: 3 mos - 50 yo | (rocephin or cefotaxime) + vanc + Dex
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PEP for meningitis | post exposure prophylaxis = rifampin for household contacts/droplet exp only; alts = cipro or rocephin
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Created by:
Abarnard
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