CHAPTER 87
Quiz yourself by thinking what should be in
each of the black spaces below before clicking
on it to display the answer.
Help!
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| show | Most commonly used agents,
•Gentamicin, tobramycin, amikacin
Narrow-spectrum antibiotics
Bactericidal
Use: Aerobic gram-negative bacilliCan cause serious injury to inner ear and kidney
Not absorbed from GI tract
Microbial resistance
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| Adverse effects general anesthetics, and in myasthenia gravis | show 🗑
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| Other adverse effects | show 🗑
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| Drug interactions | show 🗑
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| Serum Levels trough levels must be low enough to minimize toxicity | show 🗑
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| show | should be taken 30 minutes after giving an IM injection or after completing a 30-minute IV infusion
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| TROUGH LEVELS? for trough levels depends on the dosing schedule | show 🗑
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| show | Divided doses: Take sample just before the next dose •Once-daily doses: Draw a single sample 1 hour before the next dose; value should be very low—preferably close to zero
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| show | Used to treat serious infections caused by aerobic gram-negative bacilli
•Pseudomonas aeruginosa•Escherichia coli•Klebsiella•Serratia•Proteus mirabilis
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| Adverse effects | show 🗑
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| show | Tobramycin Amikacin Neomycin
Kanamycin Streptomycin
Paromomycin
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| show | Tinnitus
Ototoxicity can result from accumulation of the drug in the inner ear. Early signs that should be reported include tinnitus or headache.
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| The nurse is reviewing laboratory values from a patient who has been prescribed gentamicin. To prevent ototoxicity, it is most important for the nurse to monitor which value(s)? | show 🗑
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| Before administering gentamycin, it is most important for the nurse to assess the patient for a history of what? | show 🗑
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| The patient is ordered daily divided doses of gentamycin. The patient received an intravenous dose of gentamycin at 4:00 PM. When should the nurse obtain the peak level? | show 🗑
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