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CM- pulm -2- Asthma 1&2

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Question
Answer
What is the pathogenesis of Asthma   chronic inflammatory disease IgE combines with antigen triggering histamine release causing leaky venules, increased airway secretion stimulates irritant receptors and vagal release of ACH causing BRONCHOconstriction  
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What are the assoicated s/sx of asthma   coughing, wheezing, breathlessness and chest tightness.  
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Are the s/sx of asthma reversible   usually reversible  
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What innate immunity response can cause ashtma   TH1 and TH2 type cytokine responses  
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What environmental factors can cause asthma   airborne allergens, viral respiratory infections  
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what is the triad of asthma   Dyspnea, Cough, Wheezing  
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When are asthma symptoms worse   worse at night or early morning  
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When running spirometry what will you administer to check for asthma   give a bronchodilator looking for 12% improvement pre vs post bronchodilator  
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What are the biomarkers for inflammation in asthma   eosinophils and sputum  
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What are the treatment goals with asthma   reduce impairment reduce risk- prevent exacerbations  
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what are the four components of asthma care   1 asses severity and control of asthma 2 EDUCATION 3 control environmental factors and comorbid conditions 4 Medications  
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When thinking of impairment from asthma what should come to mind   current problems such as night time awakenings, activity limitations  
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When thinking of risks and asthma what should come to mind   think of risks as future problems controlling future frequency and exacerbation of asthma or occurence of tx related adverse effects  
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Does increased impairment from asthma equate to an increase in asthma risk   no  
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Assess severity to _______ Therapy and Assess control to ________ therapy   Assess severity to initiate Therapy and Assess control to adjust therapy  
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in component 2 of asthma treatment, education, what do you want to accomplish   ensure the family and patient understand basic facts about asthma, role of medication long term and short term acting medicines and controlling environmental conditions like possibly getting rid of a pet or smoking or other habits  
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What comorbid conditions can exacerbate asthma   GERD, Obesity, OSA, rhinnitis/sinusitis, stress/depression  
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What are the long term medications for treating asthma   corticosteroids, mast cell stablilizers, immunomodulators, leukotriene modifiers, LABA salmetrol and formoterol, methylxanthines  
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What are the short acting meds for asthma tx   anticholinergics SABAs- albuterol, levalbuterol pirbuterol systemic corticosteroids  
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after giving a tx for asthma what should you do   follow up and evaluate the controls see if you need to step up treatment or if you can step down tx  
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If you aren't getting the desired control of the asthmas what should you look at   review pt's compliance if compliance is ok step up medications consider alternative diagnosis  
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what would be considered mild asthma   dyspnea only with activity  
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what would be considered moderate asthma   dyspnea interferes or limits usual activity  
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What would be considered severe asthma   dyspnea at rest or interferes with conversation  
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what would be considered life threatening asthma   too dyspneic to speak or perspiring  
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