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Exam 3

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Question
Answer
What is the difference between ischemia and infarction?   Ischemia is reversible and infarction is cell death due to lack of oxygen and isn't reversible.  
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What is the difference between chronic stable angina vs unstable angina?   Chronic: is predictable and reversible with rest and nitro Unstable: Occurs at rest or on exertion, causes severe activity restrictions. Pain lasts longer than 15 min. and is poorly relieved with rest and nitro  
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What are the three categories of acute coronary syndrome?   STEMI, Non-stemi and unstable angina  
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What is the difference between a NSTEMI and a STEMI?   NSTEMI: Have ST and T wave changes indicating ischemia (T wave inversion) STEMI: ST elevation and possible deep Q wave/inverted T wave. Indicates rupture of plaque and thrombus causing a 100% blockage  
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What is infarction?   Develops over several hours, areas can become necrotic and becomes scar tissue causing HF and dysrhythmias  
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What causes a "widow maker"?   The LAD becomes obstructed resulting in a MI which effects the left ventricle wall, has a high rate of mortality.  
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What type of medications are used to treat chronic stable angina?   Nitroglycerin: Isosorbide, Isodril Anti-platelet aggregators: aspirin, plavix Beta Blockers: metropolol Ace inhibitors and ARB's  
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How do Ace inhibitors and ARB's help with Chronic angina?   Reduce the injection fraction, afterload  
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What is the benefit of a long acting Nitroglycerin (Isosorbide or Isodril)?   Not as much of a headache as compared to sublingual Nitro  
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What are s/s of angina?   -Substernal chest discomfort: radiating to left arm, precipitated by exertion/stress, relieved by nitro or rest, lasting less then 15 minutes  
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What are the S/S of an MI?   -Pain or discomfort: substernal chest/pain pressure radiating to the left arm, jaw, back, shoulder or abdomen. Occurs without cause, usually in the morning, relieved only by opioids , lasting 30 min or more. -Other frequent symptoms: N/V, diaphoresis, dy  
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What cardiac markers are commonly used for diagnosing an MI?   Troponin: 1-3 hours will increase CK-MB: 4-6 hr increase Myoglobin  
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What ECG changes would you see with ischemia?   ST segment depression and/or T wave inversion  
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What ECG changes would you see with a start of an injury?   ST elevation  
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What ECG change would indicate an infarction and that an occlusion and myocardial tissue has died?   Deep Q wave and inverted T wave  
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What are the immediate interventions for a STEMI?   -Sent to cath lab for angioplasty: If not in hospital; 12 hours from start of symptoms in house: goal is 90 min. Transfer from other hospital 120 min. -If unable to get to Cath lab administer TPA with in 30 min. of arrival  
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What are the immediate interventions for a NSTEMI?   -Serial EKG every 15-30 min for first hour -Serial Cardiac markers: 3 and 6 hours and then troponin levels daily while in hospital -PCI/Stenting if still symptomatic  
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What is the immediate hospital/nursing intervention for a STEMI/NSTEMI?   -Oxygen: keep at 90% min, -Aspirin: chewable 162-325 mg -Nitroglycerin: Subl Q5x3 -Morphine: for pain relief if nitro not effective  
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What medications would you expect to be ordered for a suspected STEMI/NSTEMI?   -Nitroglycerin: vasodilation -Beta Blockers: unless sign of HF/shock/asthmatic (CCB if Beta Blockers contraindicated) -Ace inhibitors: indefinitely with pt. with EF<40% and those with HTN, DM or kidney disease -Clopidogrel (plavix) or ticagrelor -Lov  
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