ANTICOAGULANT (Heparins/Parenteral)
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Indication | Peripheral arterial occlusion
VTE , ACS, DIC
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Contraindication | Thrombocytopenia (with great care), risk of bleeding, severe hepatic/renal impairment,
History of heparin-induced thrombocytopenia
Hypersensitivity
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Adverse effects | Bleeding, pain at the injection site, bruising, hyperkalemia, mild reversible thrombocytopenia
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Dose/ Route | SC, IV
No MI bc of risk of hematoma
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Mode of action | inactivate clotting factors IIa (thrombin) and Xa by binding to antithrombin III,
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