Atypical anxiolytic/nonbarbiturate anxiolytic
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| Buspirone | TX: panic disorder, social anxiety disorder, OCD, trauma & stressor-related disorders, PTSD
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| Buspirone advantage | dependency is less likely, no sedation, does not potentiate the effects of other CNS depressants
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| Buspirone disadvantage | antianxiety effect develop slowly. initial responses take a week.
full effect takes at least 2 - 6 weeks
should be taken on a schedules basis, not suitable for PRN usage
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| Buspirone complications | dizziness, nausea, headache, lightheadedness, agitation, constipation, suicidal ideation. A/Es are self-limiting.
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| buspirone contraindications/precautions | don't give to breastfeeding women
cautious w/older adults & clients w/liver or renal dysfunction.
don't with MAOI antidepressant for 14 days after MAOI is discontinued.
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| Buspirone interactions | erythromycin, ketoconazole, st. john's wort, grapefruit juice - all increase effects of buspirone.
increased risk for serotonin syndrome w/SSRIs
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| Buspirone RN adm. | take med w/meals. initial effects take a week. full effects take
2- 6 weeks. take on regular basis, not PRN.
tolerance, dependence or withdrawal effects are not an issue with this med.
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