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Drug Therapy

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Answer
Absorption   Process where a drug is taken up from the site of administration and is transported to the blood stream. Occurs orally, topically, rectally, parenteral, or by inhalation.  
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Distribution   Process where a drug, once in the bloodstream is delivered to specific organs and tissues in the body to exert its pharmacological effects.  
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Metabolism   Disappearance of a drug, when it changes chemically into another compound. Occurs in many body organs, but primarily in the liver. Usually enhances excretion and inactivation of a drug.  
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Excretion   Process by which the drug is eliminated from the body - primarily by the kidney. Drugs can be excreted via the urine, feces, lungs, skin. etc.  
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Bioavailability   This is a percentage or fraction of the administered dose of a drug that actually reaches systemic circulation. Factors affecting oral route of administration include age, body weight and time of administration.  
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Therapeutic Incompatibility   When the effectiveness of two drugs is decreased when given together.  
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Therapeutic Duplication   When two drugs from the same class are given together.  
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Adverse Effects   Effects other than the desired ones.  
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Anaphylactic Reaction   A severe adverse reaction to the administration of a drug that can cause a patient to go into shock.  
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