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Drug Therapy
Question | Answer |
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Absorption | Process where a drug is taken up from the site of administration and is transported to the blood stream. Occurs orally, topically, rectally, parenteral, or by inhalation. |
Distribution | Process where a drug, once in the bloodstream is delivered to specific organs and tissues in the body to exert its pharmacological effects. |
Metabolism | Disappearance of a drug, when it changes chemically into another compound. Occurs in many body organs, but primarily in the liver. Usually enhances excretion and inactivation of a drug. |
Excretion | Process by which the drug is eliminated from the body - primarily by the kidney. Drugs can be excreted via the urine, feces, lungs, skin. etc. |
Bioavailability | This is a percentage or fraction of the administered dose of a drug that actually reaches systemic circulation. Factors affecting oral route of administration include age, body weight and time of administration. |
Therapeutic Incompatibility | When the effectiveness of two drugs is decreased when given together. |
Therapeutic Duplication | When two drugs from the same class are given together. |
Adverse Effects | Effects other than the desired ones. |
Anaphylactic Reaction | A severe adverse reaction to the administration of a drug that can cause a patient to go into shock. |