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Drug Therapy

QuestionAnswer
Absorption Process where a drug is taken up from the site of administration and is transported to the blood stream. Occurs orally, topically, rectally, parenteral, or by inhalation.
Distribution Process where a drug, once in the bloodstream is delivered to specific organs and tissues in the body to exert its pharmacological effects.
Metabolism Disappearance of a drug, when it changes chemically into another compound. Occurs in many body organs, but primarily in the liver. Usually enhances excretion and inactivation of a drug.
Excretion Process by which the drug is eliminated from the body - primarily by the kidney. Drugs can be excreted via the urine, feces, lungs, skin. etc.
Bioavailability This is a percentage or fraction of the administered dose of a drug that actually reaches systemic circulation. Factors affecting oral route of administration include age, body weight and time of administration.
Therapeutic Incompatibility When the effectiveness of two drugs is decreased when given together.
Therapeutic Duplication When two drugs from the same class are given together.
Adverse Effects Effects other than the desired ones.
Anaphylactic Reaction A severe adverse reaction to the administration of a drug that can cause a patient to go into shock.
Created by: CTE-ECOT