Pharmacology and the Nursing Process
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| The three potassium-sparing diuretics? | spironolactone (Aldactone)
amiloride
triamterene
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| MOA of k-sparing diuretic | works by blocking aldosterone receptors; decreases resorption of Na/H2O & increases K
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| Therapeutic uses for k-sparing diuretics? | CHF; reverse K loss; hyper-aldosteronism
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| SE of k-sparing diuretic? | hyperkalemia; HA; dizziness, cramps, N/V/D
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| Contraindications of k-sparing diuretic | ACE inhibitors: increases K (hyperkalemia)
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| drugs that accelerate urine formation | diuretic
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| Example of osmotic diuretics | mannitol (Osmitrol) also prototype
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| special factors associated with mannitol? | administered IV by filter; crystalizes w/ low temp.
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| MOA of osmotic diuretic | remove Na/H2O; increases osmotic pressure of glomerular filtrate, pulls water into renal tubules
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| Indications of osmotic diuretics | renal failure; decreases ICP and intraoculuar pressure
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| osmotic diuretics considered tx for? | cerebral edema and head trauma
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| off label uses for spironolactone | gynecomastia; amenorrhea; irregular menses; postmenopausal bleeding
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| carbonic anhydrase inhibitor example? | acetazolamide
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| therapeutic uses for carbonic anhydrase inhibitor? | open angle glaucoma; heart failure edema that hasn't responded to other diuretics; high altitude sickness
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Created by:
spham
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