Musculoskeletal
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each of the black spaces below before clicking
on it to display the answer.
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| Aspirin | Brand name: Bayer, Aspirin
Func. Class: Nonopioid analgesic
Chem. Class: Salicylate
Action: Blocks pain impulses by blocking COX-1 in CNS, reduces inflammation by inhibition of prostaglandin synthesis
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| Diclofenac | Brand name: Voltaren
Func. Class: Nonsteroidal antiinflammatory drug (NSAID), nonopioid analgesic
Chem. Class: Phenylacetic acid
Action: Inhibits COX-1, COX-2 by blocking arachidonate, resulting in analgesic, antiinflammatory, antipyretic effects
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| Ibuprofen | Brand name: Advil
Func. Class: NSAID
Action: Inhibits COX-1, COX-2 by blocking arachidonate; analgesic, antiinflammatory, antipyretic
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| Naproxen | Brand Name: Aleve
Func. Class: Nonsteroidal antiinflammatory, nonopioid analgesic
Chem. Class: Propionic acid derivative
Action: Completely inhibits COX-1, COX-2 by blocking arachidonate; analgesic, antiinflammatory, antipyretic
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| Meloxicam | Brand Name: Mobic
Func. Class: NSAID
Action: analgesic NSAID for pain
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| Celecoxib | Brand Name: Celebrex
Func. Class: Nonsteroidal antiinflammatory, antirheumatic
Chem. Class: COX-2 inhibitor
Action: Inhibits prostaglandin synthesis by selectively inhibiting cyclooxygenase 2 (COX-2), an enzyme needed for biosynthesis
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| Acetaminophen | Brand Name: Tylenol
Func. Class: Nonopioid analgesic
Chem. Class: Nonsalicylate, paraaminophenol derivative
Action: May block pain impulses peripherally that occur in response to inhibition of prostaglandin synthesis; no antiinflammatory properties
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| Morphine | Brand Name: Kadian
Func. Class: Opioid Analgesic
Chem. Class: Alkaloid
Action: Depresses pain impulse transmission at the spinal cord level by interacting with opioid receptors
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| Hydrocodone Bitartrate/Acetaminophen | Brand Name: Vicodin
Func. Class: Antitussive opioid analgesic/ nonopioid
Action: acts directly on cough center in medulla to suppress cough; binds to opiate receptors in the CNS to reduce pain
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| Oxycodone | Brand Name: Oxycontin
Func. Class: Opiate analgesic
Chem. Class: semisynthetic derivative
Action: Inhibits ascending pain pathways in CNS, increases pain threshold, alters pain perception
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| Tramadol Hydrochloride | Brand name: ultram
Func. Class: mixed opioid receptor analgesic DEA schedule IV
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| Sumatriptan | Brand Name: imitrex
Func. Class: antimograine agent
Chen class: 5-HT1 receptor agonist
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| Alendronate Sodium | Brand name: Fosamax
Func. Class: bisphosphate for osteoporosis
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| Baclofen | Brand name: lioresal
Func. Chem: skeletal muscle relaxant, central acting
Chem. Class: GABA, chlorophenyl derivative
Action: inhibits synaptic responses in CNS by stimulating GABA receptor sub type
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| Carisoprodol | Name Brand: Soma
Func. Class: skeletal muscle relaxant, central acting
Chem. Class: meprobmate congener
Action: depresses CNS by blocking interneuronal activity in descending reticular formation of spinal cord, producing sedation
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| Cyclobenzaprine Hydrochlorid | Brand name: flexeril
Func. Class: skeletal muscle relaxant, central acting
Chem. Class: tricylic amine salt
Action: reduction of tonic muscle activity at the brain stem; may be related to antidepressant effects
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| Methocarbamol | Brand Name: Robaxin
Func. class: skeletal muscle relaxant
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| Tizanidine | Brand Name: Zanaflex
Func. class.: Skeletal muscle relaxant, central acting
Chem. class.: Imidazole
Action: Increases presynaptic inhibition of motor neurons and reduces spasticity by α2-adrenergic agonism
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| Allopurinol | Brand Name: Zyloprim
Func. class.: Antigout drug, antihyperuricemic
Chem. class.: Xanthine enzyme inhibitor
Action: Inhibits the enzyme xanthine oxidase, reducing uric acid synthesis
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