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Musculoskeletal

TermDefinition
Aspirin Brand name: Bayer, Aspirin Func. Class: Nonopioid analgesic Chem. Class: Salicylate Action: Blocks pain impulses by blocking COX-1 in CNS, reduces inflammation by inhibition of prostaglandin synthesis
Diclofenac Brand name: Voltaren Func. Class: Nonsteroidal antiinflammatory drug (NSAID), nonopioid analgesic Chem. Class: Phenylacetic acid Action: Inhibits COX-1, COX-2 by blocking arachidonate, resulting in analgesic, antiinflammatory, antipyretic effects
Ibuprofen Brand name: Advil Func. Class: NSAID Action: Inhibits COX-1, COX-2 by blocking arachidonate; analgesic, antiinflammatory, antipyretic
Naproxen Brand Name: Aleve Func. Class: Nonsteroidal antiinflammatory, nonopioid analgesic Chem. Class: Propionic acid derivative Action: Completely inhibits COX-1, COX-2 by blocking arachidonate; analgesic, antiinflammatory, antipyretic
Meloxicam Brand Name: Mobic Func. Class: NSAID Action: analgesic NSAID for pain
Celecoxib Brand Name: Celebrex Func. Class: Nonsteroidal antiinflammatory, antirheumatic Chem. Class: COX-2 inhibitor Action: Inhibits prostaglandin synthesis by selectively inhibiting cyclooxygenase 2 (COX-2), an enzyme needed for biosynthesis
Acetaminophen Brand Name: Tylenol Func. Class: Nonopioid analgesic Chem. Class: Nonsalicylate, paraaminophenol derivative Action: May block pain impulses peripherally that occur in response to inhibition of prostaglandin synthesis; no antiinflammatory properties
Morphine Brand Name: Kadian Func. Class: Opioid Analgesic Chem. Class: Alkaloid Action: Depresses pain impulse transmission at the spinal cord level by interacting with opioid receptors
Hydrocodone Bitartrate/Acetaminophen Brand Name: Vicodin Func. Class: Antitussive opioid analgesic/ nonopioid Action: acts directly on cough center in medulla to suppress cough; binds to opiate receptors in the CNS to reduce pain
Oxycodone Brand Name: Oxycontin Func. Class: Opiate analgesic Chem. Class: semisynthetic derivative Action: Inhibits ascending pain pathways in CNS, increases pain threshold, alters pain perception
Tramadol Hydrochloride Brand name: ultram Func. Class: mixed opioid receptor analgesic DEA schedule IV
Sumatriptan Brand Name: imitrex Func. Class: antimograine agent Chen class: 5-HT1 receptor agonist
Alendronate Sodium Brand name: Fosamax Func. Class: bisphosphate for osteoporosis
Baclofen Brand name: lioresal Func. Chem: skeletal muscle relaxant, central acting Chem. Class: GABA, chlorophenyl derivative Action: inhibits synaptic responses in CNS by stimulating GABA receptor sub type
Carisoprodol Name Brand: Soma Func. Class: skeletal muscle relaxant, central acting Chem. Class: meprobmate congener Action: depresses CNS by blocking interneuronal activity in descending reticular formation of spinal cord, producing sedation
Cyclobenzaprine Hydrochlorid Brand name: flexeril Func. Class: skeletal muscle relaxant, central acting Chem. Class: tricylic amine salt Action: reduction of tonic muscle activity at the brain stem; may be related to antidepressant effects
Methocarbamol Brand Name: Robaxin Func. class: skeletal muscle relaxant
Tizanidine Brand Name: Zanaflex Func. class.: ​Skeletal muscle relaxant, central acting Chem. class.: ​Imidazole Action: Increases presynaptic inhibition of motor neurons and reduces spasticity by α2-adrenergic agonism
Allopurinol Brand Name: Zyloprim Func. class.: Antigout drug, antihyperuricemic Chem. class.: Xanthine enzyme inhibitor Action: Inhibits the enzyme xanthine oxidase, reducing uric acid synthesis
Created by: lvnpharm