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Musculoskeletal
| Term | Definition |
|---|---|
| Aspirin | Brand name: Bayer, Aspirin Func. Class: Nonopioid analgesic Chem. Class: Salicylate Action: Blocks pain impulses by blocking COX-1 in CNS, reduces inflammation by inhibition of prostaglandin synthesis |
| Diclofenac | Brand name: Voltaren Func. Class: Nonsteroidal antiinflammatory drug (NSAID), nonopioid analgesic Chem. Class: Phenylacetic acid Action: Inhibits COX-1, COX-2 by blocking arachidonate, resulting in analgesic, antiinflammatory, antipyretic effects |
| Ibuprofen | Brand name: Advil Func. Class: NSAID Action: Inhibits COX-1, COX-2 by blocking arachidonate; analgesic, antiinflammatory, antipyretic |
| Naproxen | Brand Name: Aleve Func. Class: Nonsteroidal antiinflammatory, nonopioid analgesic Chem. Class: Propionic acid derivative Action: Completely inhibits COX-1, COX-2 by blocking arachidonate; analgesic, antiinflammatory, antipyretic |
| Meloxicam | Brand Name: Mobic Func. Class: NSAID Action: analgesic NSAID for pain |
| Celecoxib | Brand Name: Celebrex Func. Class: Nonsteroidal antiinflammatory, antirheumatic Chem. Class: COX-2 inhibitor Action: Inhibits prostaglandin synthesis by selectively inhibiting cyclooxygenase 2 (COX-2), an enzyme needed for biosynthesis |
| Acetaminophen | Brand Name: Tylenol Func. Class: Nonopioid analgesic Chem. Class: Nonsalicylate, paraaminophenol derivative Action: May block pain impulses peripherally that occur in response to inhibition of prostaglandin synthesis; no antiinflammatory properties |
| Morphine | Brand Name: Kadian Func. Class: Opioid Analgesic Chem. Class: Alkaloid Action: Depresses pain impulse transmission at the spinal cord level by interacting with opioid receptors |
| Hydrocodone Bitartrate/Acetaminophen | Brand Name: Vicodin Func. Class: Antitussive opioid analgesic/ nonopioid Action: acts directly on cough center in medulla to suppress cough; binds to opiate receptors in the CNS to reduce pain |
| Oxycodone | Brand Name: Oxycontin Func. Class: Opiate analgesic Chem. Class: semisynthetic derivative Action: Inhibits ascending pain pathways in CNS, increases pain threshold, alters pain perception |
| Tramadol Hydrochloride | Brand name: ultram Func. Class: mixed opioid receptor analgesic DEA schedule IV |
| Sumatriptan | Brand Name: imitrex Func. Class: antimograine agent Chen class: 5-HT1 receptor agonist |
| Alendronate Sodium | Brand name: Fosamax Func. Class: bisphosphate for osteoporosis |
| Baclofen | Brand name: lioresal Func. Chem: skeletal muscle relaxant, central acting Chem. Class: GABA, chlorophenyl derivative Action: inhibits synaptic responses in CNS by stimulating GABA receptor sub type |
| Carisoprodol | Name Brand: Soma Func. Class: skeletal muscle relaxant, central acting Chem. Class: meprobmate congener Action: depresses CNS by blocking interneuronal activity in descending reticular formation of spinal cord, producing sedation |
| Cyclobenzaprine Hydrochlorid | Brand name: flexeril Func. Class: skeletal muscle relaxant, central acting Chem. Class: tricylic amine salt Action: reduction of tonic muscle activity at the brain stem; may be related to antidepressant effects |
| Methocarbamol | Brand Name: Robaxin Func. class: skeletal muscle relaxant |
| Tizanidine | Brand Name: Zanaflex Func. class.: Skeletal muscle relaxant, central acting Chem. class.: Imidazole Action: Increases presynaptic inhibition of motor neurons and reduces spasticity by α2-adrenergic agonism |
| Allopurinol | Brand Name: Zyloprim Func. class.: Antigout drug, antihyperuricemic Chem. class.: Xanthine enzyme inhibitor Action: Inhibits the enzyme xanthine oxidase, reducing uric acid synthesis |
Created by:
lvnpharm
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