Terminology
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Carcinogicity | the ability of a substance to cause cancer
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Hypersensitivity | an abnormal sensitivity generally resulting in an allergic reaction
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Idiosyncrasy | an unexpected reaction the first time a drug is taken, generally due to genetic causes
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Complexation | when two different molecules associate of attach too each other
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Displacement | a drug that is bound to a plasma protein is removed when another drug of greater binding potential binds to the same protein
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Enzyme Induction | the increase of hepatic enzyme activity that results in greater metabolism of drugs
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Enzyme inhibition | the decrease of hepatic enzyme activity that results in reduced metabolism of drugs
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Additive Effects | the summation in effect when two drugs with similar pharmaceutical actions are taken
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Antidote | a drug that antagonizes the toxic effect of another
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Pharmacogenomics | field of study that defines the hereditary basis of individual differences in ADME
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Cirrhosis | a chronic liver disease causing loss of function
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Hyperthyroidism | a condition in which the thyroid secretions are above normal (overactive thyroid)
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Hypothyroidism | a condition In which thyroid hormone secretions are below normal
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obstructive jaundice | an obstruction of bile duct that causes hepatic waste products and bile accumulate in the liver
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Adverse drug reaction | an unintended side effect of a medication that is negative
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Anaphylactic shock | a potentially fatal hypersensitivity reaction producing severe respiratory distress and cardiovascular collapse
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Potentiation | when one drug with no inherent activity of its own increases the activity of another drug that produces an effect
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Synergism | when two drugs with similar pharmacological actions produce greater effects than the sum of individual effects
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Drug-diet interactions | when elements of ingested nutrients interact with a drug and this affects the disposition of the drug
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Created by:
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