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Chapter 29 White blood cell disorders Multiple Myeloma

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Multiple Myeloma   – Malignancy in which plasma cells multiply uncontrollably  
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Pathophysiology of Multiple Myeloma   – Cells infiltrate bone marrow, lymph nodes, and spleen. – Affected bones are weakened (susceptible to fracture). – Pathologic fractures  
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Manifestations of Multiple Myeloma   – Bone pain – Rapid bone destruction – Hypercalcemia – Manifestations of neurologic dysfunction – Recurrent infections – Renal failure – Pancytopenia  
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Diagnostic tests for Multiple Myeloma   – X-rays – Bone marrow examination – CBC – Protein electrophoresis – Serum calcium, creatinine, uric acid, and BUN levels – Urinalysis – Biopsy  
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Treatment for Multiple Myeloma   – No cure – Induction chemotherapy – Stem cell transplant – Maintenance chemotherapy – Combination chemotherapy – Localized radiation therapy – Plasma exchange therapy  
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Nursing Diagnoses for Multiple Myeloma   – Chronic Pain – Impaired Physical Mobility – Risk for Injury  
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