adenosine, mag sulfate, epi, calcium, neo,
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| Epinephrine GENERIC NAME | Epinephrine
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| Epinephrine BRAND NAME | Adrenalin
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| Epinephrine CLASS | Sympathomimetic
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| Epinephrine MECHANISM OF ACTION | Increased BP, HR, and bronchodilates by binding with bothalpha and beta receptors
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| Epinephrine INDICATIONS | Bronchospasms, Allergic and anaphylactic reactions, and Cardiac arrest.
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| Epinephrine CONTRAINDICATIONS | Hypertension, hypothermia, pulmonary edema, myocardial ischemia, Hypovolemic shock.
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| Epinephrine ADVERSE REACTIONS | Anxiety, nervousness, tremors, CP, arrhythmias, HTN, N/V, HA
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| Epinephrine NOTES ON ADMINISTRATION | Pregnancy safety C. May increase myocardial oxygen demand.
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| Epinephrine INCOMPATABILITIES/DRUG INTERACTIONS | Potentiates other sympathomimetics, deactivated by alkaline solutions (i.e. sodium bicarbonate) monamine oxidase inhibitors may potentiate effects.
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| Epinephrine DOSE/ROUTE, Adult, Mild allergic reactions and asthma | 0.3-0.5 mg of 1;1000 SC.
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| Epinephrine Dose/Route, Adult Anaphylaxis | 0.1mg of 1:10,000 iv/io over 5min.
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| Epinephrine Dose/Route, Ault Cardiac arrest IV/IO dose | 1 mg of 1;10,000 every 3-5 minutes during resuscitation. Follow each dose with 20 mL flush and elevate arm for 10-20 secs.
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| Epinephrine Dose/Route.Pediatric Mild allergic reactions and asthma | 0.01 mg/kg of 1;1,000 solution SC.
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| Epinephrine Dose/Route Pediatric Cardiac arrest | IV/IO dose 0.01 mg/kg of 1;10,000 solution every 3-5 minutes during arrest.
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| Epinephrine ONSET OF ACTION | Immediate.
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| Epinephrine PEAK EFFECTS | Minutes.
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| Epinephrine DURATION OF ACTION | Several minutes.
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| Epinephrine AZ DRUG BOX SUPPLY RANGE | 1:1,000 = 30 mg Multidose Vial.1:10,000 = 5 mg.
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| Neo-synephrine GENERIC NAME | PHENYLEPHRINE NASAL SPRAY 0.5%
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| Neo-synephrine BRAND NAME | Neo-synephrine Nasal Spray 0.5%
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| Neo-synephrine CLASS | Topical vasoconstrictor
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| Neo-synephrine MECHANISM OF ACTION | Stimulates a receptors in the blood vessels of the nasal mucosa which causes their constriction and thereby decreases the risk of nasal bleeding.
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| Neo-synephrine INDICATIONS | Facilitation of nasotracheal intubation
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| Neo-synephrine CONTRAINDICATIONS | Known allergy to medication
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| Neo-synephrine ADVERSE REACTIONS | Hypertension, palpitations, Tremors
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| Neo-synephrine NOTES ON ADMINISTRATION | none
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| Neo-synephrine INCOMPATABILITIES/DRUG INTERACTIONS | none
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| Neo-synephrine DOSE/ROUTE,ADULTS | 2-4 sprays in each nostril before attempting tube insertion
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| Neo-synephrine DOSE/ROUTE Peds | None
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| Neo-synephrine ONSET OF ACTION | Seconds
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| Neo-synephrine PEAK EFFECTS | 30 minutes
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| Neo-synephrine DURATION OF ACTION | 30minutes to 4 hours
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| Neo-synephrine AZ DRUG BOX SUPPLY RANGE | 1 Bottle
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| Mag GENERIC NAME | None
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| Mag BRAND NAME | Magnesium Sulfate
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| Mag CLASS | Electrolyte
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| Mag MECHANISM OF ACTION | It controls seizures by blocking peripheral neuromuscular transmission, and is also a peripheral vasodilator and an inhibitor of platelet function.
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| Mag INDICATIONS | Torsades De Points, arrhythmias associated with hypomagnesemia, Eclampsia, and prophylactically in preeclampsia, and Status Astmaticus
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| Mag CONTRAINDICATIONS | Heart blocks, GI obstruction, renal impairment.
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| Mag ADVERSE REACTIONS | facial flushing, diaphoresis, hypotension, hypothermia, weakness, muscle paralysis, and cardiac, cns, and respiratory depression
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| Mag NOTES ON ADMINISTRATION | Pregnancy category B. Recommended that this drug not be given in the 2 hours before delivery, if possible.
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| Mag INCOMPATABILITIES/DRUG INTERACTIONS | May enhance the effects of other CNS depressants
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| Mag DOSE/ROUTE Adult, Seizure activity associated with pregnancy | 1-4g IV/IO over 3 minutes. Maximum dose of 40g per day.
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| Mag DOSE/ROUTE Adult, Cardiac arrest due to hypomagnesemia or torsade de pointes | 1-2g diluted in 10ml of D5W IV/IO over 5-20 minutes.
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| Mag DOSE/ROUTE Adult, Torsade de pointes with a pulse or AMI with Hypomagnesemia | Loading dose of 1-2g mixed in 50-100 ml in D5W over 5-60 minutes IVZ.
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| Mag DOSE/ROUTE Pediatric, IV/IO infusion | 25-50 mg/kg (max dose 2g) over 10-20 minutes. Faster for torsade de pointes.
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| Mag DOSE/ROUTE Pediatric, for asthma | 25-50mg/kg over 10-20 minutes. Max dose 2g
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| Mag ONSET OF ACTION | IV/IO immediate. IM 3-4 hours.
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| Mag PEAK EFFECTS | N/A
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| Mag DURATION OF ACTION | 30 minutes IV/IO, 3-4 hours
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| Mag IM AZ DRUG BOX SUPPLY RANGE | 5g.
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| Calcium Chloride GENERIC NAME | none
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| Calcium Chloride BRAND NAME | Calcium Chloride
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| Calcium Chloride CLASS | Electrolyte
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| Calcium Chloride MECHANISM OF ACTION | Increases cardiac contractile state (positive inotropic effect)
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| Calcium Chloride INDICATIONS | 1. Hypoglycemia 2. Hyperkalemia 3. Magnesium sulfate overdose 4. Calcium channel blocker overdose
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| Calcium Chloride CONTRAINDICATIONS | 1. Hypercalcemia 2. V-fib 3. Digitalis toxicity
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| Calcium Chloride ADVERSE REACTIONS | 1. Bradycardia, 2. Asystole. 3. Hypotension 4.Peripheral Vasodilation. 5. Local necrosis. 6. Nausea and Vomiting.
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| Calcium Chloride NOTES ON ADMINISTRATION | Pregnancy safety C.
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| Calcium Chloride INCOMPATABILITIES/DRUG INTERACTIONS | May worsen arrhythmias secondary to digitalis toxicity. May antagonize the effects of verapamil.
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| Calcium Chloride DOSE/ROUTE Adult | 500-1000mg (5-10 ml of a 10% solution) IV/IO May be repeated as needed.
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| Calcium Chloride DOSE/ROUTE Pediatric | 20mg/kg slow IV/IO push. Maximum 1 gram dose. May be repeated in 10 minutes.
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| Calcium Chloride ONSET OF ACTION | 3-5 minutes
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| Calcium Chloride PEAK EFFECTS | 5-15 minutes.
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| Calcium Chloride DURATION OF ACTION | 4 hours (dose dependent).
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| Calcium Chloride AZ DRUG BOX SUPPLY RANGE | 1 Gram
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| Adenosine GENERIC NAME | Adenosine
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| Adenosine BRAND NAME | Adenocard
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| Adenosine CLASS | Endogenous nucleotide
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| Adenosine MECHANISM OF ACTION | Slows conduction of the electrical impulses at the AV node
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| Adenosine INDICATIONS | Stable reentry SVT
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| Adenosine CONTRAINDICATIONS | Sick sinus syndrome, second or third degree heart block, Poison or drug induced tachycardia.
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| Adenosine ADVERSE REACTIONS | Sense of impending doom, flushing, chest pressure, throat tightness, Numbness, may cause a brief episode of Asystole after administration
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| Adenosine NOTES ON ADMINISTRATION | Pregnancy category C. Short half life
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| Adenosine INCOMPATABILITIES/DRUG INTERACTIONS | May cause Bronchoconstriction in asthmatic patients, Tegretol may block the effects of adenosine.
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| Adenosine DOSE/ROUTEAdult | 6mg over 1-3 seconds followed by a 20ml saline flush. If no response after 1-2 minutes repeat with a dose of 12mg over 1-3 seconds. If no change repeat 12mg over 1-3 sec. Total dose 30mg.
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| Adenosine DOSE/ROUTE Peds. | 0.1-0.2 mg/kg rapid IV. Max single dose 12mg.
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| Adenosine ONSET OF ACTION | seconds
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| Adenosine PEAK EFFECTS | seconds
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| Adenosine DURATION OF ACTION | 12 seconds
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| Adenosine AZ DRUG BOX SUPPLY RANGE | 30mg
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