pharmacology, nurs 101
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Barbiturates MOA | reduce nerve impulses to cerebral cortex (block impulses)
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Barbiturates Indication | hypnotic, sedative, anticonvulsant
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Benzodiazepines MOA | depress activity in hypothalmus, thalmus, & limbic system (GABA)
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Benzodiazepines Indication | sedation, sleep induction, muscle relaxant, decrease anxiety. Lesser- etoh withdrawl, depression, epilepsy
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Benzodiazepines interactions | kava kava, grapefruit juice
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Muscle relaxants MOA | majority depress the nerve transmission in the spinal cord. Dantrolent acts directly on the exicitation-contraction of the muscle fibers
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Muscle relaxant indication | relieves painful MS conditions and muscle spasams
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Nursing Process CNS hypnontic sedatives | A:mental status, sleep diary, VSS, neuro assessments
DX: gas exchange, knowledge, sleep, injury
O: free of resp, depression, injury, & normal sleep
I: Monitor safety, sleep, abuse, toxicity
E: improve sense of well being, decreased spasitcity
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What class of drugs are in the hypnotic/sedative group? | barbiturates, benzodiazepines, muscle relaxants
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ADHD/Narcolepsy Agents MOA | stimulate areas of the cerebral cortex and thalamus associated w/ mental alertness. Increase norepi and dopamine synapses and block reuptake.
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ADHA/Narcolepsy indications | treat ADHA and nacrcolepsy
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Anorexiants MOA | supress appetite control centers in brain. Inhibit reuptake of dopamine, norepi, and serotonin.
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Anorexiants indications | used to treat obesity
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Barbituates adverse effects | -Drowsiness/lethargy
-paradoxal restlessness/excitement
-deprivation of REM sleep
-toxic overdose results in respiratory depression/arrest coma or death
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Benzodiazepines adverse effects | -headache
-drowsiness
-lethargy
-paradoxal restlessness
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