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Neuropathology

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Question
Answer
What is NCS/EMG used for?   To reveal lower motor neuron phenomenon  
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Injury or disease of the nerve is called?   neuropathy  
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Injury and or disease of the muscle is called?   myopathy  
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What are three types of myopathy?   genetically determined, toxic, and inflammatory  
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Can peripheral nerves regenerate?   yes  
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If these are destroyed peripheral nerves cant regenerate.   perikaryons  
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The perikaryon is also known as the what?   cell body  
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The axon grows at a rate of ______.   1-3mm/day  
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Nerve fiber distal to the injury degenerates along with its myelin sheath = ?   wallerian degeneration  
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After nerve injury what does the nucleus do?   moves to the periphery  
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After nerve injury what happens to the nissl bodies?   they become greatly reduced  
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Three weeks post nerve injury muscle fibers show pronounced atrophy secondary to ________.   denervation  
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About how long does it take for the nerve fiber to regenerate?   3 months  
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neurapraxia, axonotmesis, neurotmesis, all are considered axonal degeneration neuropathies...which form of nerve classification does this describe?   seddon  
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five degrees, based on pathology and EMG/NCS changes...which form of nerve classification does this describe?   Sunderland  
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Conduction loss (temporary or transient block) without structural loss of the axon – mildest form of nerve block is what?   neurapraxia 1st degree  
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What are common causes of neurapraxia 1st degree?   compresison, ischemia, ionic changes of the nerve fibers  
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With neurapraxia, recovery takes place within _______ following removal of the cause.   days or weeks  
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Axons lose continuity with subsequent wallerian degeneration along the distal segment followed by denervation-induced muscle atrophy is called?   axonotmesis  
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With axonotmesis conduction ceases ________ across the site of the nerve injury.   imeediatly  
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With axonotmesis there is _________ loss of excitability first at the neuromuscular junction then the distal nerve segment.   irreversible  
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Axonotmesis recovery depends on what and can take how long.   regeneration of nerve fibers, can take months to years  
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an injury that separates the entire nerve, including the supporting connective tissue is called?   neurotmesis  
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If pt's with nerotmesis do not have _______ _______, regeneration proceeds slowly, resulting in an incomplete and poorly organized repair.   surgical intervention  
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In neurotmesis, what kind of response do you get with a NCS?   No response with stimulation proximal or distal to the lesion (motor or sensory)  
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Degeneration of muscle fibers and infiltration by CT resulting in progressive muscle weakness is?   myotonia  
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myotonic discharges (trains of PWs) provoked by voluntary contraction or moving the needle - wax and wane (“divebomber”) NCS normal...what does this describe?   myotonia  
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Created by: txst spr 2009
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