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Electrophysiology
Neuropathology
| Question | Answer |
|---|---|
| What is NCS/EMG used for? | To reveal lower motor neuron phenomenon |
| Injury or disease of the nerve is called? | neuropathy |
| Injury and or disease of the muscle is called? | myopathy |
| What are three types of myopathy? | genetically determined, toxic, and inflammatory |
| Can peripheral nerves regenerate? | yes |
| If these are destroyed peripheral nerves cant regenerate. | perikaryons |
| The perikaryon is also known as the what? | cell body |
| The axon grows at a rate of ______. | 1-3mm/day |
| Nerve fiber distal to the injury degenerates along with its myelin sheath = ? | wallerian degeneration |
| After nerve injury what does the nucleus do? | moves to the periphery |
| After nerve injury what happens to the nissl bodies? | they become greatly reduced |
| Three weeks post nerve injury muscle fibers show pronounced atrophy secondary to ________. | denervation |
| About how long does it take for the nerve fiber to regenerate? | 3 months |
| neurapraxia, axonotmesis, neurotmesis, all are considered axonal degeneration neuropathies...which form of nerve classification does this describe? | seddon |
| five degrees, based on pathology and EMG/NCS changes...which form of nerve classification does this describe? | Sunderland |
| Conduction loss (temporary or transient block) without structural loss of the axon – mildest form of nerve block is what? | neurapraxia 1st degree |
| What are common causes of neurapraxia 1st degree? | compresison, ischemia, ionic changes of the nerve fibers |
| With neurapraxia, recovery takes place within _______ following removal of the cause. | days or weeks |
| Axons lose continuity with subsequent wallerian degeneration along the distal segment followed by denervation-induced muscle atrophy is called? | axonotmesis |
| With axonotmesis conduction ceases ________ across the site of the nerve injury. | imeediatly |
| With axonotmesis there is _________ loss of excitability first at the neuromuscular junction then the distal nerve segment. | irreversible |
| Axonotmesis recovery depends on what and can take how long. | regeneration of nerve fibers, can take months to years |
| an injury that separates the entire nerve, including the supporting connective tissue is called? | neurotmesis |
| If pt's with nerotmesis do not have _______ _______, regeneration proceeds slowly, resulting in an incomplete and poorly organized repair. | surgical intervention |
| In neurotmesis, what kind of response do you get with a NCS? | No response with stimulation proximal or distal to the lesion (motor or sensory) |
| Degeneration of muscle fibers and infiltration by CT resulting in progressive muscle weakness is? | myotonia |
| myotonic discharges (trains of PWs) provoked by voluntary contraction or moving the needle - wax and wane (“divebomber”) NCS normal...what does this describe? | myotonia |