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Antiinfectives

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Term
Definition
Penicillin Target   Bactericidal, Cell Wall, Beta-Lactam Ring  
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Penicillin Used For   Pneumonia, meningitis, skin, bone, joint infection, stomach infections, blood and valve infections, gas gangrene  
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Cephalosporins Target   Gram negative, cell wall synthesis inhibition  
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Cephalosporins Used For   Pseudomonas, klepsiella, Neisseria, Salmonella, Proteus, H. influenzae. MRSA  
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Tetracyclines Target   Bacteriostatic, Protein synthesis. One of broadest spectrum Gram - and Gram +  
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Tetracyclines Used For   Rocky mountain spotted fever, tuphus, cholera, Lyme disease, peptic ulcers caused by H. pylori, chlamydial infections  
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Tetracyclines Special Considerations   Dispose promptly of expired doses. Avoid taking with calcium or magnesium, antacids, or milk due to 50% decrease in absorption  
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Macrolides Target   Bacteriostatic, protein synthesis inhibition. Active against most gram + and many gram -  
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Macrolides Used For   Whooping cough, legionnaires' disease, streptococcus bacteria infections  
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Macrolides Special Considerations   Give with glass of water on empty stomach. Do not give with or immediately before or after fruit juices  
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Aminoglycocides Target   Bactericidal, Inhibit protein synthesis, Aerobic Gram-, mycobacteria, some brotozoans  
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Aminoglycocides Used For   Given for local effect on GI tract, sometimes given with a penicillin, cephalosporin, vancomycin to treat enterococcal infection  
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Fluroquinolones Target   Bacteriocidal, DNA synthesis, Gram -  
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Fluroquinolones Used For   Respiratory infections, GI and genitourinary tracts. Preffered for treatment of uncomplicated UTIs. Used against exposure to anthrax or other biological warfare pathogens  
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Fluroquinolones Special Consideerations   Avoid multivitamins or mineral supplements because calcium, magnesium, iron, or zinc ions can reduce absorption by 90%  
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Sulfonamides Target   Bacteriostatic, folic acid inhibitor. Gram - and Gram +  
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Sulfonamides Used For   Concentrated by kidneys. Prevent infections in burn patients with topical. Pneumocystis carnii pneumonia, shigella infections of the bowel  
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Carbapenems Target   Bactericidal, broadest antimicrobial spectrums. Contain beta-lactam. Inhibiting cell wall  
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Carbapenems Special Considerations   Can only be given parenterally  
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Penicillin Names   Penicillin G benzathine, nafcillin, oxacillin  
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Cephalosporins Names   Cefadroxil, cefalcor, cefotetan, cefdinir, cefditoren  
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Tetracyclines Names   Demeclocycline, doxycycline, minocycline  
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Macrolides Names   Azithromycin, clarithromycin, erythromycin  
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Aminoglycocides Names   Amikacin, kanamycin, neomycin, streptomycin  
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Fluroquinolones Names   Ciprofloxacin, norfloxacin, ofloxacin  
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Sulfonamides   Sulfadiazine, sulfadoxine, sulfisoxazole  
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Created by: mochimochi49
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