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Antiinfectives

TermDefinition
Penicillin Target Bactericidal, Cell Wall, Beta-Lactam Ring
Penicillin Used For Pneumonia, meningitis, skin, bone, joint infection, stomach infections, blood and valve infections, gas gangrene
Cephalosporins Target Gram negative, cell wall synthesis inhibition
Cephalosporins Used For Pseudomonas, klepsiella, Neisseria, Salmonella, Proteus, H. influenzae. MRSA
Tetracyclines Target Bacteriostatic, Protein synthesis. One of broadest spectrum Gram - and Gram +
Tetracyclines Used For Rocky mountain spotted fever, tuphus, cholera, Lyme disease, peptic ulcers caused by H. pylori, chlamydial infections
Tetracyclines Special Considerations Dispose promptly of expired doses. Avoid taking with calcium or magnesium, antacids, or milk due to 50% decrease in absorption
Macrolides Target Bacteriostatic, protein synthesis inhibition. Active against most gram + and many gram -
Macrolides Used For Whooping cough, legionnaires' disease, streptococcus bacteria infections
Macrolides Special Considerations Give with glass of water on empty stomach. Do not give with or immediately before or after fruit juices
Aminoglycocides Target Bactericidal, Inhibit protein synthesis, Aerobic Gram-, mycobacteria, some brotozoans
Aminoglycocides Used For Given for local effect on GI tract, sometimes given with a penicillin, cephalosporin, vancomycin to treat enterococcal infection
Fluroquinolones Target Bacteriocidal, DNA synthesis, Gram -
Fluroquinolones Used For Respiratory infections, GI and genitourinary tracts. Preffered for treatment of uncomplicated UTIs. Used against exposure to anthrax or other biological warfare pathogens
Fluroquinolones Special Consideerations Avoid multivitamins or mineral supplements because calcium, magnesium, iron, or zinc ions can reduce absorption by 90%
Sulfonamides Target Bacteriostatic, folic acid inhibitor. Gram - and Gram +
Sulfonamides Used For Concentrated by kidneys. Prevent infections in burn patients with topical. Pneumocystis carnii pneumonia, shigella infections of the bowel
Carbapenems Target Bactericidal, broadest antimicrobial spectrums. Contain beta-lactam. Inhibiting cell wall
Carbapenems Special Considerations Can only be given parenterally
Penicillin Names Penicillin G benzathine, nafcillin, oxacillin
Cephalosporins Names Cefadroxil, cefalcor, cefotetan, cefdinir, cefditoren
Tetracyclines Names Demeclocycline, doxycycline, minocycline
Macrolides Names Azithromycin, clarithromycin, erythromycin
Aminoglycocides Names Amikacin, kanamycin, neomycin, streptomycin
Fluroquinolones Names Ciprofloxacin, norfloxacin, ofloxacin
Sulfonamides Sulfadiazine, sulfadoxine, sulfisoxazole
Created by: mochimochi49