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Antiinfectives
Term | Definition |
---|---|
Penicillin Target | Bactericidal, Cell Wall, Beta-Lactam Ring |
Penicillin Used For | Pneumonia, meningitis, skin, bone, joint infection, stomach infections, blood and valve infections, gas gangrene |
Cephalosporins Target | Gram negative, cell wall synthesis inhibition |
Cephalosporins Used For | Pseudomonas, klepsiella, Neisseria, Salmonella, Proteus, H. influenzae. MRSA |
Tetracyclines Target | Bacteriostatic, Protein synthesis. One of broadest spectrum Gram - and Gram + |
Tetracyclines Used For | Rocky mountain spotted fever, tuphus, cholera, Lyme disease, peptic ulcers caused by H. pylori, chlamydial infections |
Tetracyclines Special Considerations | Dispose promptly of expired doses. Avoid taking with calcium or magnesium, antacids, or milk due to 50% decrease in absorption |
Macrolides Target | Bacteriostatic, protein synthesis inhibition. Active against most gram + and many gram - |
Macrolides Used For | Whooping cough, legionnaires' disease, streptococcus bacteria infections |
Macrolides Special Considerations | Give with glass of water on empty stomach. Do not give with or immediately before or after fruit juices |
Aminoglycocides Target | Bactericidal, Inhibit protein synthesis, Aerobic Gram-, mycobacteria, some brotozoans |
Aminoglycocides Used For | Given for local effect on GI tract, sometimes given with a penicillin, cephalosporin, vancomycin to treat enterococcal infection |
Fluroquinolones Target | Bacteriocidal, DNA synthesis, Gram - |
Fluroquinolones Used For | Respiratory infections, GI and genitourinary tracts. Preffered for treatment of uncomplicated UTIs. Used against exposure to anthrax or other biological warfare pathogens |
Fluroquinolones Special Consideerations | Avoid multivitamins or mineral supplements because calcium, magnesium, iron, or zinc ions can reduce absorption by 90% |
Sulfonamides Target | Bacteriostatic, folic acid inhibitor. Gram - and Gram + |
Sulfonamides Used For | Concentrated by kidneys. Prevent infections in burn patients with topical. Pneumocystis carnii pneumonia, shigella infections of the bowel |
Carbapenems Target | Bactericidal, broadest antimicrobial spectrums. Contain beta-lactam. Inhibiting cell wall |
Carbapenems Special Considerations | Can only be given parenterally |
Penicillin Names | Penicillin G benzathine, nafcillin, oxacillin |
Cephalosporins Names | Cefadroxil, cefalcor, cefotetan, cefdinir, cefditoren |
Tetracyclines Names | Demeclocycline, doxycycline, minocycline |
Macrolides Names | Azithromycin, clarithromycin, erythromycin |
Aminoglycocides Names | Amikacin, kanamycin, neomycin, streptomycin |
Fluroquinolones Names | Ciprofloxacin, norfloxacin, ofloxacin |
Sulfonamides | Sulfadiazine, sulfadoxine, sulfisoxazole |