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PharmT2

Quiz yourself by thinking what should be in each of the black spaces below before clicking on it to display the answer.
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Question
Answer
Flecainide   most used rhythm control of atrial arrhythmias  
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Acyclovir   effective ob only HSV express enzyme for efficient activation  
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Ivermectin   activates Glu-gated Cl channel  
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mild OrganoPO4 exposure AE   cycloplegia, diaphoresis, urinary urgency, miosis  
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mild OrganoPO4 exposure AE   not xerostomia, mydriasis, constipation  
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Digoxin   t1/2=1.5-2d, drug excreted unchanged by kidney  
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Chloroquine resistant prophylaxis   does not = Bactrim [Sulfa-Trimeth]  
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Chloroquine resistant prophylaxis   Mefloquine, Atovaquine, Doxycycline  
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Amlodipine   prevents stable angina, most import MOA dilation of resist a.[dec afterload]  
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Ranolazine [Anti-Ischemic]   AE: syncope, arrhythmia  
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class II   Beta adrenergic R  
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Pt tx w/ rhythm control drugs   has more normal hemodynamics  
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Metoprolol   prophylaxis of stable angina, least effective on variant angina  
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Andenosine [Anti-arrhyth]   has MOA depend on drug induced H-polarization of A-V node  
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Albuterol   increased heart contractile F and decreased Aw Resist  
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Metoprolol   add to CHF tx of Losartan+Furosemide if Lv struct and sx worsen  
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Metoprolol+Renolazine   for prophylaxis of angina. Pt: severe angina at rest+ isch. Ht dz  
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Lidocaine   tx Pt w/ hypoTN, dec CO, Vtach, tx Vtach w/o inc HTN  
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Hydroclorothiazide [HCTZ]   Pt w/ HTN on Nifedipine, got wt gain  
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Verapamil   induce inc Atrial rate, slow/nl Vent, prolonged P-R  
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AE: Inc Fascic->paralysis post anesth   Succhinoyl choline- Pt has reduced butyrylcholine Enz activity  
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Amlodipine+Metoprolol   best Anti-Isch for freq stable angina not prevented w/ 1 drug  
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Hydroclorothiazide [HCTZ]   Pt w/ HTN and poor  
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elderly   dec dose ob dec metab and distribution  
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Triamterene   blocks Na channels in distal nephron, produce inc K+  
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Mannitol   inc plasma volume, tx cerebral edema  
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Nicotinic+Muscarinic R   affected by chemical warfare agent  
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Propanolol   tx HTN, CHF, Isch ht dz  
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Dobutamine   tx CHF [only] not HTN  
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losartan   tx HTN, CHF  
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Propanolol   tx HTN, AE: bradycardia, exacerbate Aw dz  
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Tolterodone   tx Night time eneurisis in kids  
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Dantrolene   dec Ca intracell thru Ryanodine-R  
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Vancomycin inc   Erythromycin  
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Ranolazine [Anti-Ischemic]   AE: syncope, arrhythmia  
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Adenosine   Anti-Arrhythmic, HyperPolarization of A-V node  
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Isch ht drug, angina at rest. Metoprolol ineffective   Metoprolol+Ranolazine  
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Hepatic schizontocide   Primaquine  
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Verapamil   Vtach and AE: Atrial Fib, prolong P-R interval  
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AE: Torsades de Ponte   Procainamide  
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