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OPT Salivary

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Term
Definition
mucocele (mucus extravasation phenomenon)   rupture of salivary gland duct with mucus spillage into soft tissues; most frequently in anterior and lower lip  
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ranula   mucocele in the floor of the mouth  
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plunging/cervical ranula   occurs when mucus dissects through mylohyoid and produces sweeping of the neck  
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superficial mucocele   mucus accumulates right under surface epithelium and produces clear, small vesicles; common in posterior buccal mucosa and soft palate  
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salivary gland duct cyst (mucus duct cyst, sialocyst)   epithelium-lined cavity that arises from salivary gland tissue but does not communicate with the lumen of the duct; contains watery fluid in the regions of the salivary ducts  
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sialolith   dystrophic calcifications in salivary gland ducts, unrelated to blood calcium levels  
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sialadenitis   inflammation of salivary glands from various causes; often Staph aureus and mumps  
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surgical mumps   sialadenitis and enlargement in patients given atropine while NPO during surgical procedures  
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acute sialadenitis   pain, swelling, purulence of salivary glands; usually bacterial and in parotid gland  
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chronic sialadenitis   secondary to persistent salivary gland duct obstruction, usually from sialoliths; sialograms exhibit "sausaging" of Stensen's duct  
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juvenile recurrent parotitis   most common salivary disorder in kids; recurring episodes of parotid swelling  
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cheilitis glandularis   rare inflammatory disorder of labial minor salivary glands of unknown cause but probably sun damage  
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xerostomia   subjective sensation of dry mouth, usually in females  
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Sjogren syndrome   chronic systemic autoimmune disorder of salivary and lacrimal glands resulting in dry mouth and eyes -{primary Sjogren}- process occurs alone -{secondary Sjogren}- in conjunction with rheumatoid arthritis or lupus  
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sicca syndrome   combination of dry mouth and eyes  
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benign lymphoepithelial lesion   histologic pattern of Sjogren affected gland; acinar atrophy, lymphocytic infiltrate and residual ductal epithelium  
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epimyoepithelial islands   duct cells and myoepithelial cells become hyperplastic and form these surrounded by lymphocytic infiltrate in Sjogren's  
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Mikulicz disease   bilateral parotid and lacrimal gland enlargement due to benign lymphoepithelial lesions  
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Mikulicz syndrome   any bilateral enlargement of parotid and lacrimal glands  
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Schirmer test   strips of filtered paper that are placed in lower eyelid to gauge tear production  
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adenomatoid hyperplasia   idiopathic process that affects hard and soft palates with painless, benign enlargements  
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necrotizing sialometaplasia   secondary to ischemia of salivary tissue that leads to infarction and necrosis, 75% in posterior palate; often misdiagnosed as mucoepidermoid carcinoma but is benign and resolves in 5-6 weeks  
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pleomorphic adenoma (benign mixed tumor)   most common salivary gland neoplasm; mixture of ductal and myoepithelial cells, painless, slow-growing, benign mass of considerable size  
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Warthin tumor (papillary cyst adenoma lymphomatosum)   firm benign mass at tail of parotid/angle of mandible; associated with smoking  
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canalicular adenoma   uncommon benign tumor in minor salivary glands, especially upper lip  
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basal cell adenoma   uncommon benign neoplasm of basal cell layer of salivary gland ducts; 75% in parotid gland, most arise de novo  
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mucoepidermoid carcinoma   most common malignant salivary gland tumor, can be in kids and mostly in parotid; can be confused with mucocele  
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intraosseous mucoepidermoid carcinoma   uncommon malignant neoplasm from omnipotential odontogenic epithelium; develop with impacted teeth or odontogenic cysts, usually in the mandible  
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acinic cell carcinoma   low-grade malignancy of mature-appearing serous acinar cells; can occur in kids  
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malignant mixed tumors   malignant counterparts of benign pleomorphic adenoma with 3 patterns  
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carcinoma ex pleomorphic adenoma   transformation of previously benign pleomorphic adenoma, usually after 15 years; a malignant mixed tumor  
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carcinosarcoma   rare malignant mixed tumor of epithelial and stromal malignancies  
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metastasizing mixed tumor   malignant mixed tumor that appears benign but exhibits metastasis in bones and lungs  
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adenoid cystic carcinoma (cylindroma)   common malignancy of salivary glands with basaloid epithelial cells arranged in {cribriform/Swiss cheese pattern} and exhibits {perineurial invasion}  
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cribriform / Swiss cheese pattern   arrangement of cells in adenoid cystic carcinoma; also exhibits {perineurial invasion)  
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polymorphous low-grade adenocarcinoma   malignant salivary gland tumor, almost always in minor salivary glands with cells in many different patterns  
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salivary adenocarcinoma, NOS   salivary gland carcinomas that defy existing classification scheme; 'trash bag' of unknown diagnoses  
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