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Review of key items on respiratory medication

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Question
Answer
Action of beta adrenergic agonists   stimulate beta-2 receptors in the SNS causing bronchodilation  
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Location of beta 1 receptors   heart  
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Location of beta 2 receptors   lungs  
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Three pharmaceutical classes of bronchodilators   beta-adrenergic agonists or anticholinergic, and Xanthines  
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Inhaled drugs-onset, duration   rapid onset, short duration  
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Action of Xanthine   smoothe muscle relaxant, inhibits phosphodiesterase  
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Examples of xanthine bronchodilators   theophylline (Theodur or TheoCap), Aminophylline, caffeine  
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Side effects of xanthine drugs   toxicity, tachycardia, restlessness and insomnia, seizures, anorexia, give with meals  
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Action of Anticholinergics   blocks parasympathetic input, decreases bronchial constriction, not used for acute attacks!  
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Side effects of anticholinergics   dry secretions, urinary retention, NOT used in clients with glaucoma or urinary obstructions  
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Action of corticosteroids   decreases the inflammatory and immune responses  
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Systemic corticosteroids examples   prednisone and methylprednisone  
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What to avoid with systemic corticosteroids   never ever stop abruptly, and taper when switching from systemic to inhaled steroids  
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Side effects of corticosteroids   weight gain, electrolyte imbalances(decreased Potassium), hypertension, hyperglycemia from decreased effects of diabetic agents, thin skin, decreased healing, bone loss  
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important teaching for inhaled steroids   rinse mouth after use, and wash chamber and mouthpiece! combo drug inhaled via dry powder  
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Mast cell stabilizers (antiinflammatory agent)   inhibit mast cells from busting open and releasing substances that cause inflammation. Cromolyn (Intal) nedocromil (Tilade )  
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Antitussives action   cough suppressants  
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Narcotic Antitussives   codeine, hydrocodone  
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Side-effects for antitussives   sedation, dry mouth, constipation, check for adequate hydration  
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Mucolytics and Expectorants action   thins out and loosens secretions, making them easier to expectorate  
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These drugs can be used in the ACUTE phase of an Asthmatic attack   Bronchodilators  
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What types of patients should bronchodilators be cautioned in because it has an adverse effect   Patients with heart disease  
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Drug ending for beta 1 agonist   "erol"  
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Drug ending for anticholingeric   'pium"  
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Beta-adrenergic agonist (ie: albuterol) side-effects.   CNS stimulation: increased appetite, blood glucose, and blood pressure, and pulse  
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Created by: tgwin7
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