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Respiratory Drugs
Review of key items on respiratory medication
| Question | Answer |
|---|---|
| Action of beta adrenergic agonists | stimulate beta-2 receptors in the SNS causing bronchodilation |
| Location of beta 1 receptors | heart |
| Location of beta 2 receptors | lungs |
| Three pharmaceutical classes of bronchodilators | beta-adrenergic agonists or anticholinergic, and Xanthines |
| Inhaled drugs-onset, duration | rapid onset, short duration |
| Action of Xanthine | smoothe muscle relaxant, inhibits phosphodiesterase |
| Examples of xanthine bronchodilators | theophylline (Theodur or TheoCap), Aminophylline, caffeine |
| Side effects of xanthine drugs | toxicity, tachycardia, restlessness and insomnia, seizures, anorexia, give with meals |
| Action of Anticholinergics | blocks parasympathetic input, decreases bronchial constriction, not used for acute attacks! |
| Side effects of anticholinergics | dry secretions, urinary retention, NOT used in clients with glaucoma or urinary obstructions |
| Action of corticosteroids | decreases the inflammatory and immune responses |
| Systemic corticosteroids examples | prednisone and methylprednisone |
| What to avoid with systemic corticosteroids | never ever stop abruptly, and taper when switching from systemic to inhaled steroids |
| Side effects of corticosteroids | weight gain, electrolyte imbalances(decreased Potassium), hypertension, hyperglycemia from decreased effects of diabetic agents, thin skin, decreased healing, bone loss |
| important teaching for inhaled steroids | rinse mouth after use, and wash chamber and mouthpiece! combo drug inhaled via dry powder |
| Mast cell stabilizers (antiinflammatory agent) | inhibit mast cells from busting open and releasing substances that cause inflammation. Cromolyn (Intal) nedocromil (Tilade ) |
| Antitussives action | cough suppressants |
| Narcotic Antitussives | codeine, hydrocodone |
| Side-effects for antitussives | sedation, dry mouth, constipation, check for adequate hydration |
| Mucolytics and Expectorants action | thins out and loosens secretions, making them easier to expectorate |
| These drugs can be used in the ACUTE phase of an Asthmatic attack | Bronchodilators |
| What types of patients should bronchodilators be cautioned in because it has an adverse effect | Patients with heart disease |
| Drug ending for beta 1 agonist | "erol" |
| Drug ending for anticholingeric | 'pium" |
| Beta-adrenergic agonist (ie: albuterol) side-effects. | CNS stimulation: increased appetite, blood glucose, and blood pressure, and pulse |