Coumadin Interaction
Quiz yourself by thinking what should be in
each of the black spaces below before clicking
on it to display the answer.
Help!
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Barbiturates | Induce CYP3A4, CYP1A2, CYP2C9
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Carbamazepine | Induce CYP3A4, CYP1A2, CYP2C9
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Cigarette Smoke | Induce CYP1A2
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Phenytoin | Indcue CYP3A4, CYP1A2, CYP2C9
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Rifampin | Induce CYP3A4, CYP1A2, CYP2C9
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Griseofulvin | Induce CYP3A4
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Nafcillin/Dicloxacillin | Induce CYP3A4
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Azathioprine | Inducer (unknown)
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Cimetidine | Inhibit CYP1A2
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Ciprofloxacin | Inhibit CYP1A2
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Erythromycin | Inhibit CYP1A2, CYP3A4
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Fluvoxamine | Inhibit CYP1A2, CYP3A4
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Clarithromycin | Inhibit CYP3A4
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Fluoxetine (SSRIs) | Inhibit CYP3A4
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Grapefruit juice | Inhibit CYP3A4
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Itraconazole | Inhibit CYP3A4
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Nefazodone | Inhibit CYP3A4
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Omeprazole | Inhibit CYP3A4
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Quinidine | Inhibit CYP3A4
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Ritonavir | Inhibit CYP3A4
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Statins | Inhibit CYP3A4
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Tetracycline | Inhibit CYP3A4
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Tygacil | Inhibit CYP3A4
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Zafirlukasst | Inhibt CYP3A4, CYP2C9
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Amiodarone | Inhibit CYP2C9
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Disulfuram | Inhibit CYP2C9
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Metronidazole | Inhibit CYP2C9
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TMP/SMZ | Inhibit CYP2C9
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Cranberry juice | Inhibit CYP2C9
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Dong Quai | Increase INR
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Papain | Increase INR
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Ginkgo and ginseng | Increased bleeding
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Garlic and giner | Increased bleeding
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Coenzyme Q-10 | Decrease INR
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St. John's Wort | Decrease INR
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Green Tea | Decrease INR
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Enzyme Inducers | Decreased INR
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Enzyme Inhibitors | Increased INR
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Created by:
Bmiller01
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