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Coumadin Interaction

QuestionAnswer
Barbiturates Induce CYP3A4, CYP1A2, CYP2C9
Carbamazepine Induce CYP3A4, CYP1A2, CYP2C9
Cigarette Smoke Induce CYP1A2
Phenytoin Indcue CYP3A4, CYP1A2, CYP2C9
Rifampin Induce CYP3A4, CYP1A2, CYP2C9
Griseofulvin Induce CYP3A4
Nafcillin/Dicloxacillin Induce CYP3A4
Azathioprine Inducer (unknown)
Cimetidine Inhibit CYP1A2
Ciprofloxacin Inhibit CYP1A2
Erythromycin Inhibit CYP1A2, CYP3A4
Fluvoxamine Inhibit CYP1A2, CYP3A4
Clarithromycin Inhibit CYP3A4
Fluoxetine (SSRIs) Inhibit CYP3A4
Grapefruit juice Inhibit CYP3A4
Itraconazole Inhibit CYP3A4
Nefazodone Inhibit CYP3A4
Omeprazole Inhibit CYP3A4
Quinidine Inhibit CYP3A4
Ritonavir Inhibit CYP3A4
Statins Inhibit CYP3A4
Tetracycline Inhibit CYP3A4
Tygacil Inhibit CYP3A4
Zafirlukasst Inhibt CYP3A4, CYP2C9
Amiodarone Inhibit CYP2C9
Disulfuram Inhibit CYP2C9
Metronidazole Inhibit CYP2C9
TMP/SMZ Inhibit CYP2C9
Cranberry juice Inhibit CYP2C9
Dong Quai Increase INR
Papain Increase INR
Ginkgo and ginseng Increased bleeding
Garlic and giner Increased bleeding
Coenzyme Q-10 Decrease INR
St. John's Wort Decrease INR
Green Tea Decrease INR
Enzyme Inducers Decreased INR
Enzyme Inhibitors Increased INR
Created by: Bmiller01
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