diltiazem
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| asd | sd
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| GENERIC NAME | DILTIAZEM
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| BRAND NAME | Cardizem
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| CLASS | Calcium Channel Blocker, Calcium antagonist
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| MECHANISM OF ACTION | Inhibits calcium ion influx across cell membranes during depolarization,decreases SA&AV conduction,dilates coronary&peripheral arteries.Slows the rapid ventricular rate associated with a-fib and a-flutter,&reduces coronary&peripheral vascular resistance.
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| INDICATIONS | Rapid ventricular rates associated with atrial fibrillation and atrial flutter, and for PSVT refractory to adenosine.
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| CONTRAINDICATIONS | Hypotension(less than 90 mmHg systolic), Acute Myocardial infarction, Cardiogenic shock, Ventricular tachycardia or wide-complex VT of unknown origin, Second or third-degree AV block,(WPW) syndrome, Sick Sinus syndrome, Beta Blocker Use
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| ADVERSE REACTIONS | hypotension, Bradycardia, heart block, chest pain, and Asystole, N/V, headache, fatigue, drowsiness
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| NOTES ON ADMINISTRATION | None
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| INCOMPATABILITIES/DRUG INTERACTIONS | Avoid use in patients with poison- or drug-induced tachycardia. Calcium chloride can be used to prevent the Hypotensive effects of this drug and treat patients with a calcium channel blocker overdose.
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| Beta blocker use. |
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| DOSE/ROUTE, Adult Dosage, Initial | 0.25 mg/kg IVP (usually 20 mg) administered over 2 minutes.If response is inadequate, repeat in 15 minutes; 0.35 mg/kg IVP administered over 2 minutes
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| Adult Maintenance infusion | 5.0 to 15 mg/hr
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| Pediatric Dosage | The safety of this drug for use in children has not been established.
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| ONSET OF ACTION | IV - immediately
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| PEAK EFFECTS | IV - 2 hours or less
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| DURATION OF ACTION | IV - 4 to 6 hours
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| AZ DRUG BOX SUPPLY RANGE | 25 mg,10 mg
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Created by:
klindley
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