inhaled anesthetics, opiods, narcatiocs
Quiz yourself by thinking what should be in
each of the black spaces below before clicking
on it to display the answer.
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| Analgesia, euphoria, sedation | show 🗑
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| show | Agonist indications
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| show | Agonist Indications
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| Morphine decrease cerebral blood flow in the absence of hypoventilation | show 🗑
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| Morphine reduces what during Myocardial infarctions | show 🗑
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| show | Itching also a Agonist clinical use
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| show | Agonist-Antagonist Indications
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| trhese drugs have the ability to produce Analgesia with limited risk of ventilation and physical dependence | show 🗑
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| show | Agonist-Antagonist
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| show | Agonist-Antagonist
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| Used to treat opiod respiratory depression | show 🗑
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| Treat opiod induced respiratory depression do to maternal administration of opiods | show 🗑
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| Treat deiliberate overdose | show 🗑
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| Treat side effects of itching associated with neuraxial opiods | show 🗑
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| 5X more potent than fentanyl, 1000x more potent morphine (strongest) | show 🗑
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| show | Sufentanyl> Remifentanyl> Alfentanyl> Morphine> Meperidine
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| show | Alfentanyl> Sufentanyl> Fentanyl> Morphine> Meperidine
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| show | Morhine> Meperidine> Fentanyl> sufentanyl> Alfentanyl> remifentanyl
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| show | Fentanyl 6.4> Sufentanyl6.2> Alfentanl 1.4> Remifentanyl 1.1> Morphine 15-30 Meperidine
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| Partially reverse an agonist w/o completely reversing analgesic properties | show 🗑
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| Limited risk of ventilator depression and physical dependency | show 🗑
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| show | Agonist-Antagonist Disadvantage
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| show | Agnist-Antagonist Disadvantage
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| show | Clinical advantage of Morphine liposomal
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| show | Clinical advantage of Morphine liposomal
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| Designed for control of pain after major surgeries | show 🗑
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| show | Disadvantage of Morphine liposomal
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| show | Disadvantage of Morhine liposomal
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| Most common side effect of neuraxial opiods | show 🗑
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| show | Ventilation depression
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| show | Neuraxial Opiods
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| Neuraxial opiods __________ Mac for volatile anesthetics. | show 🗑
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| show | Neuraxial Opiods
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| show | Neuraxial Opiods
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| show | Meperidine
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| show | Meperidine
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| show | in the liver
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| What's Meperidine primary route of elimination? | show 🗑
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| Meperidine is metabolized into what | show 🗑
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| Common side effects of Morphine | show 🗑
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| show | by acting on the mu receptors
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| show | produce analgesia and uphoria
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| What is Mu2 mechanism of action | show 🗑
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| How is Remifentanyl metabolized | show 🗑
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| What are advantages of remifentanyl | show 🗑
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| show | Cost, short duration of action could be disadvantage with long painful surgeries
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| show | growth hormone
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| produced by anterior pituitary | show 🗑
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| show | Luteinizing hormone (gonadotropin)
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| show | Adrenocorticotropic hormone (ATCH)
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| produced by anterior pituitary | show 🗑
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| produced by posterior pituitary | show 🗑
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| produced by osterior pituitary | show 🗑
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| How should patients with prior hypophysectomy be treated prior, during and after surgery? | show 🗑
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| How should patients scheduled for thyroidectomy be treated before ssurgery? | show 🗑
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| What is the anti-inflammatory potency and Na retaining potency for Prednisolone? | show 🗑
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| show | Anti-inflammtory = 4 Na retaining potency = .8
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| show | Anti-inflammatory = 5 Na retaining potency = 0.5
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| show | Anti-inflammtory = 25 Na retaining potency = 0
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| What is the anti-inflammatory potency and Na retainig potency for Dexamethasone? | show 🗑
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| What is Fludricortisone | show 🗑
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| show | causes uterine contractions
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| What are the clinical uses of ADH | show 🗑
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| Suppression of HPA axis | show 🗑
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| hypokalemisa is an advrse reaction of what | show 🗑
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| show | Corticosteroids
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| hyperglycemia is an adverse reaction of what | show 🗑
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| Developement of immune defiency may be caused by? | show 🗑
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| show | Corticosteroids
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| Peripheral blood changes may be caused by? | show 🗑
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| Osteoporosis and PUD are caused by? | show 🗑
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| show | Corticosteroids
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| show | Corticosteroids
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| What precautions should be taken with a patient who has chronic hypoadrenocorticism? | show 🗑
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| Corticosteroid results in suppression of the ______ and leads to blunting normal release of | show 🗑
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| show | Increase the dosage of Corticosterods
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| show | inappropriate and excessive secretion of ADH with subsequent water retension and dilutional hyponatremia.
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| show | Head traumas, intracranial tumors, meningitis, pulmonary infections, & oat cell carcinomas
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| show | Demeclomycin (Declomycin)
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| show | Promotes diuresis by antagonizing the effects of ADH on renal tubules.
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| What are the signs and synmptoms of SIADH? | show 🗑
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| What factors speeds up induction from machine to alveoli? | show 🗑
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| What speeds up inhaled anesthetics from alveoli to arterial blood? | show 🗑
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| What speeds up induction from arterial blood to brain? | show 🗑
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| show | anesthetic concentration
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| show | uptake
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| The net effect of increasing anesthetic concentration is a more rapid increase in PA and thus and increase in the ___________? | show 🗑
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| show | rapid
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| What is the ratio of aveloalar ventilation to FCR ratio in neonates | show 🗑
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| show | 1:5
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| Indiction of anesthesia is slower with what? | show 🗑
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| show | potency/solubility, oil:gas partition coeffceient.
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| What effect does a high oil:gas partician coeffecient have? | show 🗑
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| show | High MAC or low potency
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| Define MAC | show 🗑
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| show | Hyperthermia, Hypernatremia, Hyperthyroid, chronic ETOH abuse,
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| show | Cocaine, MAOI, Ephedrine, Levadopa
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| show | Hypothermia, hyponatremia, elderly, acute alcohol ingestion, postpartum, BP<40 cardio-pulmonary bypass, anemia, metabolic acidosis hypoxia, pregnancy,
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| show | Benzos, clonidine, A2agonist, lithium, lidocaine, neuraxial oopiods,
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| show | Ketamine, Chlorpromazine, Physostigmine, Pancurium, Verapamil, Tetrahydrocanbinol hydroxine
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| show | Lungs
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| show | Gi tract and .004%
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| Deslflurane is metabolized by what and how much | show 🗑
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| Isoflurane is metabolized how and how much | show 🗑
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| show | 5% FROM P450
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| show | The higher the solubility the more the agent will diffuse into the muscles or blood, thus prolonging induction.
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| In regards to volatile anesthetics which is the most soluble agent in use? | show 🗑
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| What inhalational agent has the greatest analgesia and paralytic properties? | show 🗑
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| show | Degredation product Sevoflurane and CO2 absorbers.
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| What risks are associated with Compound A | show 🗑
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| What can be done to prevent formation of Compound A | show 🗑
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| show | When Nitrous Oxide is discont it leads to a reversal of partial pressure gradients, N2O leaves the blood and entrs the alveoli and dilutes PAO2 and PCO2 in the alveoli
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| What can be done to avoid diffusion hypoxia? | show 🗑
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| What is the MAC, blood:gas partition coeffecient of NITROUS OXIDE? | show 🗑
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| show | MAC = 1.2 B:G = 1.46 oil:gas = 98 VP = 240
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| What is the MAC, VP, B:G O:G partition coeffecient of SEVOFLURANE | show 🗑
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| What is the MAC, VP, B:G, O:G partition coeffecient of DESFLURANE | show 🗑
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| show | safer for kidneys, does not cause seizures, decrease ICP, decrease CMRO2 requirements, decrease BP but not CO,
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| show | Profound ventilation depression, tachepnia, Increased heart rate.
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| show | very pungent, airway irritant, increased coughing, increased incidence of laryngospasm, requires special heated vaporizer, decrease CO and BP, decrease cereberal blood flow
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| What are the advantages of Deflurane? | show 🗑
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| show | has no preservatives, but less stable, Reasonble MAC, non-irritating to airways, does not change heart rate.
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| What are the disadvantages of Sevoflurane? | show 🗑
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| What are the disadvantages of NO2? | show 🗑
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| What are the disadvantages of Nitrous Oxide? | show 🗑
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| What are s&s of fluoride toxicity? | show 🗑
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| What agent is fluortoxcity associated with? | show 🗑
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| show | nephrotixic
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| Currently used anesthetics have significantly less metabolism and are less soluble thus | show 🗑
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| show | Succinylchloine and volatile anesthetics
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| show | true
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| show | Halothane although it is no longer used in the states.
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| show | Nitrous Oxide
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