Diuretics for Cardiac Drugs
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| major clinical indications for these drugs are edema, HF, and hypertension | Diuretics
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| most commonly used thiazide diuretic | hydrochlorothiazide
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| only thiazide diuretic that can be give IV | chlorothiazide
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| Not effective when immediate diuresis is needed | Thiazide
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| prescribed for long term management of HF and hypertension | Thiazide
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| decrease reabsorption of sodium, water, chloride, and Bicarb in the distal convoluted tubule | Thiazides
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| diuretic effects usually occur within 1-2 hours and peak 4-6 hours | Thiazides
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| do not use in patients who are allergic to sulfa drugs | Thiazides and Loop
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| don't use if pregnant | Thiazides and Loop
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| ineffective with decreased renal function | Thiazides
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| mild thiazide | HCTZ
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| give drug in the AM | Loop and Thiazide
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| monitor sodium and chloride | Thiazide
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| CL less or equal to 30 ml/min, hold the drug | Thiazide
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| K and Mg are lost | Thiazide
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| muscle cramps | hypokalcemia
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| ppl picking at things | low Mg
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| hyperglycemia | Thiazides
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| if on Digoxin, you could have toxicity bc of the decreased K | Thiazides
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| Calcium is retained | Thiazides
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| ingesting licorice | lose K
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| ingesting ginko | Increase BP
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| can become hypercalcemia | Thiazides
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| inhibit sodium and chloride reabsorption in the AL of Henle | Loop
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| most filtered sodium is reabsorbed here | ALH
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| sodium losing effects are 10 times more effective than thiazides | Loop
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| most effective and versatile diuretic | Loop
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| diuretic effect occur within 30-60 min. peak in 1-2 hours | Loop
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| sodium restriction is required to achieve max effects of the drug | loop
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| drug accumulation does not occur even with repeated doses | Loop (the kidneys get rid of the drug)
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| immediate diuresis | Loop
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| can be used in renal impairment (CCL <30 mL.min) | Loop
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| most commonly used loop diuretic and serves as the prototype | Furoemide (Lasix)
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| may be used to produce diuresis in some patients who no longer respond to furosemide | Bumetanide (Bumex)
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| more potent Loop on a drug-weight basis, and larger doses can be given in small volumes | Bumex
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| High ceiling diuretic | Loop (Lasix)
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| uric acid levels will rise with this diuretic, so don't give to someone with gout | Loop
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| more potent if given IV push, can cause ototoxicity forever | Lasix
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| Washes out all electrolytes so hypercalcemia is not a problem | Loop
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| if patient does not diures within ________ minutes after IV push, then call they Dr. | Five
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| with oral admin. urine flow should increase within _____ min | 30 with Loop
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| will cause vasodilation and can be given to patients with renal insufficiencies | Loop
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| improve BF by _____% | 40 Loop
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| this can be given to person allergic to sulfa | Edecrin 1 gen
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| first choice for cancer patients | Loop
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| interact with war and coum | Loop
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| impacts corticosteroids, amphotericin-b, antihypertensives, and aminoglycosides | Loop
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| supplement diet or take supplements for this diuretic | loop
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