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Seizures

Quiz yourself by thinking what should be in each of the black spaces below before clicking on it to display the answer.
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Question
Answer
target phenytoin level   10-20 mg/dL  
HLA-B*1502 and HLA-A*3101 are gene mutations associated with increased risk of using which seizure medication   CBZ - HLA-B*1502 increases risk of steven johnson syndrome. most common in asians and indian patients TESTING RECOMMENDED. HLA-A*3101 increase in hypersensitivity syndrom e and maculopapular rash. north european and japanese mnostly. TESTING NOT REC.  
conversion of fosphenytoin to phenytoin equivalents   1 mg phenytoin = 1.5 mg fosphenytoin= 1 mg phenytoin equivalents  
max infusion rate for phenytoin   150 mg PE/min  
emergent drugs for status epilepticus. give to stop seizure.   diazepam, lorazepam or midazolam  
urgent drugs for status epilepticus. give after emergent meds to prevent further seizures   phenytoin, fosphenytoin, phenobarbital, valproic acid, levetiracetam, lacosamide,  
options for refractory status epilepticus   pentobarb infusion, thiopental infusion, midazolam infusion, propofol infusion  
common adverse effects for carbamazepine   hyponatremia, delayed rash, blood dyscrasias. SIADH  


   


 
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Created by: mjuhlin