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HIV

Quiz yourself by thinking what should be in each of the black spaces below before clicking on it to display the answer.
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Question
Answer
show Truvada (emtricitabine/tenofovir) 300mg/200mg QD  
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show zidovudine  
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normal CD4 count   show
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show 30%  
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show increase 50-100/mm^3 annually  
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CD4 count diagnostic of AIDS (stage 3 HIV)   show
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show documentation of an AIDS defining condition along with laboratory confirmation of HIV  
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symptoms of acute/primary HIV infection   show
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show if CD4 count <200  
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show flu, pneumococcal (once), Hep B (in all susceptible) and Hep A (if at high risk)  
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show 6 weeks with zidovudine 4 mg/kg/dose Q12H. if mom didn't take ART during preggers add nevirapine at birth and repeat at 48 hours then 96 hours after the second dose, repeat.  
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what HIV drug should be avoided in women of childbearing age to avoid first trimester exposure   show
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how long should post exposure prophylaxis continue and how soon after exposure should it start   show
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show raltegravir PLUS Truvada (emtricitabine/tenofovir) [occupational]. no preference for ART if non-occupational other than that it be potent combination ART.  
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in a low risk HIV positive pt, when should ART be initiated   show
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what are the principles of HIV opportunistic infections   show
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preferred treatment for PCP   show
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show 150-PCO2-PO2  
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show clinda + primaquine; pentamidine; trimethoprim + dapsone; atovaquone  
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show fluconazole 200 mg QD  
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show positive CSF cultures, CSF india ink, CSF cryptococcal antigen titer, elevated opening pressure >20, serum cryptococcal antigen more than 1:8  
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preferred treatment for cryptococcus meningitis   show
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treatment for CMV infections   show
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show secondary is required fo rall. can d/c when CD4 ct is >100 for 3-6 months or longer with ART. primary ppx not recommended but if cd4 ct is <50 recommend funduscopic exam regularly  
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standard therapy for toxoplasmosis   show
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prophylaxis for toxoplasmosis   show
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treatment for latent TB in pts NOT coinfected with HIV   show
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treatment for latent TB in pts coinfected with HIV   show
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show isoniazid, rifampin, pyrazinamide and ethambutol for 2 months followed by isoniazid and rifampin for 4 more months  
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treatment for active TB in pt coinfected with HIV   show
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show 1 L NS for 24 hrs or 500 ml before and after dose. avoid diuretics and liberalize salt intake  
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show dilute to 0.1 mg/ml and infuse over at least 4 hours. use a central site and may add heparin  
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show amp B induces PGE synthesis. hydrocortisone or ibuprofen may help. ASA/APAP/benadryl have not been shown to help but were also not specifically studied  
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treatment of rigors for amp B   show
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why is there no renal adjustment dose for voriconazole?   show
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show rifampin, rifabutin, carbamazepine, barbituates, sirolimus  
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show tac decrease dose by 2/3. cyclosporine decrease dose by 1/2  
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Created by: mjuhlin
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