Pharmacology Assignment 1, general pharm, drug admin and calc
Quiz yourself by thinking what should be in
each of the black spaces below before clicking
on it to display the answer.
Help!
|
|
||||
|---|---|---|---|---|---|
| Veterinarian-Client Relationship Criteria | 1. Vet assumes responsibility for making judgements and Client agrees to follow instruction
2. Vet has knowledge to diagnose
3. Vet available for follow-up eval
🗑
|
||||
| Pharmacokinetics | Complex series of events that occurs once a drug is administered to patient: Absorption, Distribution, Biotransformation, Excretion
🗑
|
||||
| Intradermal | Inj. in the skin
🗑
|
||||
| Intraperitoneal | Inj. into abdominal cavity
🗑
|
||||
| Intraarterial | Inj. into artery
🗑
|
||||
| Intraarticular | Inj. into joint
🗑
|
||||
| Intramedullary | Inj. into bone marrow cavity
🗑
|
||||
| Epidural/Subdural | Inj. into spine
🗑
|
||||
| Bioavailability | Measures amt. of drug that gets absorbed and is available to patient
🗑
|
||||
| Water-soluble | Dissolve in presence of water. Tend to stay in bloodstream
🗑
|
||||
| Lipid-soluble | Absorbed by body fats. Tend to move into interstitial fluid between organs and tissues
🗑
|
||||
| Four processes of transformation (or metabolism) | 1.Oxidation
2.Reduction
3.Hydrolysis
4.Conjugation
🗑
|
||||
| Oxidation | loss of electrons in drugs chemical makeup
🗑
|
||||
| Reduction | gain of electrons in drug's chemical makeup
🗑
|
||||
| Hydrolysis | Splitting of drug's molecule and addition of water molecules to split portion
🗑
|
||||
| Conjugation | joining together two compounds (drug and glucuronic acid) to make another compound that dissolves quicker in water
🗑
|
||||
| Half-life | the time it takes for half of the drug to be removed from the animal's system
🗑
|
||||
| Pharmacodynamics | study of mechanisms by which drugs produce physiological changes in the body (cellular level)
🗑
|
||||
| Agonist drugs | Drugs that attach to certain receptors and cause specific actions
🗑
|
||||
| antagonist drugs | Drugs that block receptors from being acted on
🗑
|
||||
| Partial agonists | Drugs that partially fit into receptors, causing partial affinity or efficacy and blocking rest of receptor
🗑
|
||||
| Efficacy | Degree to which a drug produces desired effect
🗑
|
||||
| Potency | Amount of drug needed to produce desired effect
🗑
|
||||
| Lethal Dose | Dose of drug that is lethal to 50% of animals given that drug
🗑
|
||||
| Effective dose | Dose of drug that produces desired effect in 50% of animals given that drug
🗑
|
||||
| therpeutic index | LD/ED
higher the therapeutic index, the safer the drug is
the lower, the more dangerous
🗑
|
||||
| proprietary drug name | trade name
🗑
|
||||
| generic drug | unpatented copy of drug
🗑
|
||||
| US Food and Drug Admin. (FDA) | regulates development and approval of animal drugs and feed additives through Center for Veterinary Medicine
🗑
|
||||
| Environmental Protection Agency (EPA) | regulates development and approval of animal topical pesticides
🗑
|
||||
| Drug Enforcement Agency (DEA) | regulates substances that have potential for human abuse
🗑
|
||||
| US Dept. of Ag. (USDA) | development an approval of biologics (vx, serums, antitoxins)
🗑
|
||||
| Food Animal Residue Avoidance Databank (FARAD) | produces safe foods of animal origins
🗑
|
||||
| Animal Medicinal Drug Use Clarification Act | made extralabel use of approved vet drugs legal
🗑
|
||||
| FDA policy on compounding | allows compounding of medications in order to medicate animals of various sizes, etc.
🗑
|
||||
| Veterinary Feed Directive | Gave CVMA ability to better regulate drugs that go into animal feeds
🗑
|
||||
| Four sources of drugs | 1. botanical
2.Animals
3.Laboratories
4. Bacteria and molds
🗑
|
||||
| Technician responsibilities during drug admin | 1. Correct drug
2. correct route and time
3. Animal's response
4. Question unclear orders
5. Correct label
6. Explaining orders to clients
7. Recording in record
🗑
|
||||
| 8 Factors that affect absorption process | 1. mechanism of absorption
2. pH and ionization status of drug
3. Absorptive surface area
4. Blood supply to area
5. Solubility of drug
6. Dosage form
7. Status of GI tract
8. Interaction with other meds
🗑
|
||||
| Biotransformation | body's ability to change a drug chemically from the form in which it was administered into a form that can be eliminated from the body (aka turned into a metabolite). (liver)
🗑
|
||||
| Site of drug excretion | kidneys
🗑
|
||||
| 6 things that are included on drug container label | 1. Drug names (generic and trade)
2. Drug concentration and qty.
3. Name and address of manufacturer
4. Controlled subst. status
5. Manufacturer's control of lot number
6. Expiry date
🗑
|
||||
| The Green Book | list of all animal drug products that are approved by FDA for safety and effectiveness
🗑
|
||||
| Three classes of drug interactions | 1. Pharmacodynamic
2. Pharmacokinetic
2. Pharmaceutic
🗑
|
||||
| Pharmacokinetic interaction | Plasma or tissue levels of a drug are altered by presence of another
🗑
|
||||
| Pharmacodynamic interaction | action or effect of one drug is altered by another at site of drug action
🗑
|
||||
| Pharmaceutic interaction | occurs when physical or chemical reactions take place as a result of mixing of drugs in a syringe or other container
🗑
|
||||
| ethical products | products for which manufacturer has voluntarily limited their sale to veterinarians as a marketing decision
🗑
|
||||
| Liniment | Medicinal preparations for use on the skin as a counter irritant or to relieve pain.
🗑
|
||||
| Lotions | liquid solutions or suspensions with soothing substances that are applied to skin
🗑
|
||||
| Ointment | semisolid prep of oil and water plus medical agent
🗑
|
||||
| Microencapsulated | when a protective environment is formed against harmful substances and the stability of the product is improved-masks flavor
🗑
|
||||
| Six Rights of Drug Administration | 1. Right Patient 2. Right Drug (triple check) 3. Right dose 4. Right route 5. Right time and frequency 6. Right documentation
🗑
|
||||
| Boluses | Large rectangular tablets used in treatment of large animals with aid of a balling gun.
🗑
|
||||
| An IV catheter should be flushed every _ to _ hours | 8-12 hours
🗑
|
||||
| Any patient receiving IV fluid therapy should be monitored every _ to _ minutes | 15-30 minutes
🗑
|
||||
| IV tubing should be changed after a _ to _ hour period | 48-72 hours
🗑
|
Review the information in the table. When you are ready to quiz yourself you can hide individual columns or the entire table. Then you can click on the empty cells to reveal the answer. Try to recall what will be displayed before clicking the empty cell.
To hide a column, click on the column name.
To hide the entire table, click on the "Hide All" button.
You may also shuffle the rows of the table by clicking on the "Shuffle" button.
Or sort by any of the columns using the down arrow next to any column heading.
If you know all the data on any row, you can temporarily remove it by tapping the trash can to the right of the row.
To hide a column, click on the column name.
To hide the entire table, click on the "Hide All" button.
You may also shuffle the rows of the table by clicking on the "Shuffle" button.
Or sort by any of the columns using the down arrow next to any column heading.
If you know all the data on any row, you can temporarily remove it by tapping the trash can to the right of the row.
Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.
Normal Size Small Size show me how
Normal Size Small Size show me how
Created by:
10153210848445672
Popular Pharmacology sets