MEDS
Quiz yourself by thinking what should be in
each of the black spaces below before clicking
on it to display the answer.
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| Addison disease, and decreased adrenal cortex function are treated with what medication? | Glucocorticoids
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| What type of medications increase your susceptibility to infections? | Glucocorticoids
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| What type of medication has a side effect of an increased risk of hyperglycemia, insulin resistance and decreases the control of blood glucose levels? | Glucocorticoids
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| What type of medication may have a side effect of causing glaucoma? | Glucocorticoids... note: Antimalarial drugs can also cause retinal problems
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| What type of medication may cause mood swings and psychoses? | Glucocorticoids
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| What type of medication may cause a drug induced cushings syndrome? | Glucocorticoids
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| What type of medication may have catabolic effects of the ms, bone (drug induced OP), ligaments, tendons, and skin(easy bruising)? | Glucocorticoids
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| What type of nonendocrine conditions may glucocorticoids be used for? | RA (for antiinflammatory and immunisuppressive effects), symptoms of other collagen diseases and rheumatic disorders
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| What is glucocorticoids used as? | as an anti-inflammatory agent
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| What is the mechanism of action behind glucocorticoids? | they inhibit production of prostoglandins and leukotrienes. supresses the migration of magrophages, stabilizes the lysosomal membrane, inhibits hypersensitivity and allergic reactions, acting as an immunosuppressant
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| Name some glucocorticoids | prednisone, hydrocortisone, dexamethasome, aldosterone (things that end in -one)
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| What are the pharmacological effects of acetaminophen? | analgesic, antipyretic, NOT AN ANTIINFLAMMATORY
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| What do NSAIDS do and how do they work? | anti-inflammatory, mild to moderate analgesia, antipyretic, anticoagulant, work by inhibition of prostoglandins
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| What is an advantange to COX 2 inhibitors | they mainly target cox 2 enzymes and dont really target as much cox 1 (GI tract maintenance) so you get less GI problems and the drug is more specifically geared toward inhibiting synthesis of inflammatory prostoglandins
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| What is a disadvantage to COX 2 inhibitors | you have increased risk for stroke of MI, raises BP,
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| What are some of the advantages of aspirin? | analgesic, anti-inflammatory, may prevent CA, inhibits platelet induced thrombosis..(thromboxanes, which facilitate blood clot formation)come from prostoglandins
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| What are some disadvantages to Aspirin? | GI problems, peptic ulcers, reyes syndrome in kids
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| What are some atvantages to acetaminophen | no GI irritation, OTC, may block cox3 enzyme
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| What are some disadvantages to acetaminophen | toxic to liver, esp c ETOH
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| Tylenol is a type of | acetaminophen
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| Advil is a type of.. | IBU, NSAID
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| DMARDS are more popular in what type of arthritis? | RA as well as other rheumatic conditions such as SLE, myasthenia gravis, chrones disease
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| DMARDS work by ... | inhibiting TNF, DNA RNA synthesis of the precursers of lymphocytesiting some WBC maturation, and inhib so basically it acts as an immunosuppressant.
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| What are some examples of DMARDS? | antimalarial, etanercept (TNF blocker), methotrexate (impairs DNA synthesis by inhibiting purine biosynthesis), azanthioprine (effects DNA, RNA precursers), leflunomide(inhibits RNA precursers of lymphocytes),gold therapy, penicill(tcell)
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| Etanercept(enbrel)is a type of DMARD that | TNF blocker
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| methotrexate is a type of DMARD that | impairs DNA synthesis by inhibiting purine biosynthesis),
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| azanthioprine is a type of DMARD that | (effects DNA, RNA precursers)
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| leflunomideis a type of DMARD that | inhibits RNA precursers of lymphocytes
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| gold therapy | inhibits phagocyte maturation, supresses synovial inflammation during active RA
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| penicillamine | chelator of heavy metals slows the tcell function
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| What can cause reyes syndrome in kids | asprin (NSAID)
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