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Lesson 2.1 What is Diabetes? - Key Terms:

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Term
Definition
Glucagon   A protein hormone secreted by pancreatic endocrine cells that raises blood glucose levels; an antagonistic hormone to insulin.  
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Hormone   A product of living cells that circulates in blood and produces a specific, often stimulatory, effect on the activity of cells that are often far from the source of the hormone.  
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Insulin   A protein hormone secreted by the pancreas that is essential for the metabolism of carbohydrates and the regulation of glucose levels in the blood.  
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Negative Feedback   A primary mechanism of homeostasis, whereby a change in a physiological variable that is being monitored triggers a response that counteracts the initial fluctuation.  
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Positive Feedback   Feedback that tends to magnify a process or increase its output.  
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Type 1 Diabetes   develops in childhood or adolescence and is characterized by a severe deficiency of insulin, leading to high blood glucose levels.  
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Type 2 Diabetes   develops in adults & most often obese individuals & that is characterized by high blood glucose resulting from impaired insulin utilization coupled with the body’s inability to compensate with increased insulin production.  
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Glucose Tolerance Test    
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