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Pharm chp 3

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Term
Definition
blood dyscrasia   bone marrow depression caused by drug effects on the rapidly multiplying cells of the bone marrow; lower-than-normal levels of blood components can be seen  
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dermatological reactions   skin reactions commonly seen as adverse effects of drugs; can range from simple rash to potentially fatal exfoliative dermatitis  
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drug allergy   formation of antibodies to a drug or drug protein; causes an immune response when the person is next exposed to that drug  
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hypersensitivity   excessive responsiveness to either the primary or the secondary effects of a drug; may be caused by a pathological condition or, in the absence of one, by a particular patient’s individual response  
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poisoning   overdose of a drug that causes damage to multiple body systems and has the potential for fatal reactions  
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stomatitis   inflammation of the mucous membranes related to drug effects; can lead to alterations in nutrition and dental problems  
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superinfections   infections caused by the destruction of normal flora bacteria by certain drugs, which allow other bacteria to enter the body and cause infection; may occur during the course of antibiotic therapy  
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No drug does only   what is desired of it. All drugs have adverse effects associated with them  
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Adverse drug effects   can range from allergic reactions to tissue and cellular damage. The nurse needs to assess each situation for potential adverse effects and intervene appropriately to minimize those effects  
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Adverse effects   can be extensions of the primary action of a drug or secondary effects that are not necessarily desirable but are unavoidable  
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Allergic reactions can occur   when a person’s body makes antibodies to a drug or drug protein. If the person is exposed to that drug at another time, an immune response may occur.  
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Tissue damage can include   skin problems, mucous membrane inflammation, blood dyscrasias, superinfections, liver or renal toxicity, poisoning, hypoglycemia or hyperglycemia, electrolyte disturbances, various CNS problems (ocular damage, auditory damage, atropine-like effects,  
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