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Pharm chp 3
| Term | Definition |
|---|---|
| blood dyscrasia | bone marrow depression caused by drug effects on the rapidly multiplying cells of the bone marrow; lower-than-normal levels of blood components can be seen |
| dermatological reactions | skin reactions commonly seen as adverse effects of drugs; can range from simple rash to potentially fatal exfoliative dermatitis |
| drug allergy | formation of antibodies to a drug or drug protein; causes an immune response when the person is next exposed to that drug |
| hypersensitivity | excessive responsiveness to either the primary or the secondary effects of a drug; may be caused by a pathological condition or, in the absence of one, by a particular patient’s individual response |
| poisoning | overdose of a drug that causes damage to multiple body systems and has the potential for fatal reactions |
| stomatitis | inflammation of the mucous membranes related to drug effects; can lead to alterations in nutrition and dental problems |
| superinfections | infections caused by the destruction of normal flora bacteria by certain drugs, which allow other bacteria to enter the body and cause infection; may occur during the course of antibiotic therapy |
| No drug does only | what is desired of it. All drugs have adverse effects associated with them |
| Adverse drug effects | can range from allergic reactions to tissue and cellular damage. The nurse needs to assess each situation for potential adverse effects and intervene appropriately to minimize those effects |
| Adverse effects | can be extensions of the primary action of a drug or secondary effects that are not necessarily desirable but are unavoidable |
| Allergic reactions can occur | when a person’s body makes antibodies to a drug or drug protein. If the person is exposed to that drug at another time, an immune response may occur. |
| Tissue damage can include | skin problems, mucous membrane inflammation, blood dyscrasias, superinfections, liver or renal toxicity, poisoning, hypoglycemia or hyperglycemia, electrolyte disturbances, various CNS problems (ocular damage, auditory damage, atropine-like effects, |