Biology Key Terms
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Gonads | Sex organs: ovaries in females, testes in males.
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Autosomes | Paired chromosomes present in both males and females; all chromosomes except the X and Y chromosomes.
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Sex Chromosomes | Paired chromosomes that differ between males and females, XX in females, XY in male.
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X-Linked Trait | A phenotype determined by an allele on an X chromosome.
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Pedigree | A visual representation of the occurrence of phenotype across generations.
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Y-Chromosome Analysis | Comparing sequences on the Y chromosomes to examine paternity and paternal ancestry.
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Incomplete Dominance | A form of inheritance in which heterozygotes have a phenotype that is intermediate between homozygous dominant and homozygous recessive.
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Codominance | A form of inheritance in which both alleles contribute equally to the phenotype.
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Continuous Variation | Variation in a population showing an unbroken range of phenotypes rather than discrete categories.
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Polygenic Trait | A trait whose phenotype is determined by the interaction among alleles of more than one gene.
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Multifactorial Inheritance | An interaction between genes and the environment that contributes to a phenotype or trait.
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Aneuploidy | An abnormal number of one or more chromosomes (either extra or missing copies).
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Nondisjunction | The failure of chromosomes to separate accurately during cell division; nondisjunction in meiosis leads to aneuploidy gametes.
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Trisomy 21 | Carrying an extra copy of chromosome 21; also known as Down syndrome.
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Amniocentesis | A procedure that removes fluid surrounding the fetus to obtain and analyze fetal cells to diagnose genetic disorders.
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Karyotype | The chromosomal makeup of cells. Karyotype analysis can be used to detect trisomy 21 prenatally.
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Stem Cells | Immature cells that can divide and differentiate into specialized cell types.
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Tissue | An organized group of different cell types that work together to carry out a particular function.
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Adult (Somatic) Stem Cells | Stem cells located in tissues that help maintain and regenerate those tissues.
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Cellular Differentiation | The process by which a cell specializes to carry out a specific role.
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Differential Gene Expression | The process by which genes are "turned on," or expressed, in different cell types.
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Multipotent | Describes a cell with the ability to differentiate into a limited number of cell types in the body.
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Embryonic Stem Cells | Stem cells that make up an early embryo and which can differentiate into nearly every cell type in the body.
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Blastocyst | The stage of embryonic development in which the embryo is a hollow ball of cells. Researchers can derive embryonic stem cell lines during the blastocyst stage.
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Pluripotent | Describes a cell with the ability to differentiate into nearly any cell type in the body.
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Totipotent | Describes a cell with the ability to differentiate into any cell type in the body.
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Induced Pluripotent Stem Cell | A pluripotent stem cell that was generated by manipulation of a differentiated somatic cell.
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Antibiotics | Chemicals that either kill bacteria or slow their growth by interfering with the function of essential bacterial cell structures.
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Binary Fission | A type of asexual reproduction in which one parental cell divides into two.
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Population | A group of organisms of the same species living together in the same geographic area.
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Evolution | Change in allele frequencies in a population over time.
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Fitness | The relative ability of an organism to survive and reproduce in a particular environment.
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Natural Selection | Differential survival and reproduction of individuals in response to environmental pressure that leads to change in allele frequencies in a population over time.
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Adaptation | The process by which populations become better suited to their environment as a result of natural selection.
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Directional Selection | A type of natural selection in which organisms with phenotypes at one end of a spectrum are favored by the environment.
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Stabilizing Selection | A type of natural selection in which organisms near the middle of the phenotypic range of variation are favored by the environment.
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Diversifying Selection | A type of natural selection in which organisms with phenotypes at both extremes of the phenotypic range are favored by the environment.
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Population Genetics | The study of the genetic makeup of populations and how the genetic composition of a population changes.
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Gene Pool | The total collection of alleles in a population.
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Allele Frequency | The relative proportion of an allele in a population.
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Nonadaptive Evolution | Any change in allele frequency that does not by itself lead a population to become more adapted to its environment; the causes of nonadaptive evolution are mutation, genetic drift, and gene flow.
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Genetic Drift | Random changes in the allele frequencies of a population between generations; genetic drift tends to have more dramatic effects in smaller populations than in larger ones.
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Founder Effect | A type of genetic drift in which a small number of individuals leaves one population and establishes a new population; by chance, the newly established population may have lower genetic diversity than the original population.
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Bottleneck | A type of genetic drift that occurs when a population is suddenly reduced to a small number of individuals, and alleles are lost from the population as a result.
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Gene Flow | The movement of alleles from one population to another, which may increase the genetic diversity of a population.
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Inbreeding | Mating between closely related individuals. Inbreeding does not change the allele frequency within a population, but it does increase the proportion of homozygous individuals to heterozygotes.
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Inbreeding Depression | The negative reproductive consequences for a population associated with having a high frequency of homozygous individuals possessing harmful recessive alleles.
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Hardy-Weinberg Equilibrium | The principle that, in a nonevolving population, both allele and genotype frequencies remain constant from one generation to the next.
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Hardy-Weinberg Equation | A mathematical formula that calculates the frequency of genotypes and phenotypes one would expect to find in a nonevolving population.
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Biological Species Concept | The definition of a species as a population whose members can interbreed to produce fertile offspring.
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Reproductive Isolation | Mechanisms that prevent mating (and therefor gene flow) between members of different species.
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Speciation | The genetic divergence of populations, leading over time to reproductive isolation and the formation of new species.
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