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Cardiac Output Monitoring

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Question
Answer
What is normal O2 consumption?   1 - 3 or 1 - 4 mlO2/kg/min  
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What is primarily the limiting factor in O2 delivery to the tissues?   cardiac output  
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Which has more of an effect on O2 delivery: cardiac output or FiO2?   cardiac output  
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Does hemoglobin have an impact on the amount of oxygen delivered to this tissues?   Yes! a dramatic effect; hub of 4 - 5 is when our body shifts from aerobic to anaerobic metabolism  
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_____________ is the primary compensatory mechanism that responds to an oxygenation challenge.   cardiac output  
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Cardiac output monitoring helps to provide a global picture of the patient's overall __________ status   circulatory  
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Cardiac output monitoring yields information regarding O2 _______ and O2 ________   delivery & consumption  
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CO = _______ x ________   HR x SV  
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What is the definition of stroke volume?   the amount of blood pumped per heart beat  
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What 3 things determine stroke volume?   preload, after load, & contractility  
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What is the largest determinate of preload?   venous return  
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Preload basically indicates what?   fluid volume status  
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What is after load?   systemic vascular resistance  
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What effect do most of our anesthetic drugs have on contractility?   decrease contractility  
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What is the normal value for cardiac output?   4 - 8 L/min  
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What is the normal value for stroke volume?   60 - 100 (approx 70) ml/beat  
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How do you measure cardiac output via the thermodilution method?   inject 2.5 - 10 ml of fluid colder than body temp into right atrium and PA catheter senses temperature of blood in contact with it  
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What is the relationship between the degree of temperature change and cardiac output in the thermodilution method of cardiac output measurement?   change in temperature is inversely proportional to cardiac output; (temp change minimal with high blood flow; temp change greater with minimal blood flow)  
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How do you derive the thermodilution curve?   by plotting the temperature as a function of time  
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What can cause an inaccurate cardiac output estimation via the thermodilution method?   rapid fluid bolus, respiratory variation, post-bypass pump temp drift, tricuspid valve regurgitation, high PEEP, intracardiac shunt, low flow states  
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Explain the continuous thermodilution method of cardiac output measurement.   Uses small heat signal instead of cold via a specialized PA catheter; updates CO averages every 30 seconds, average readings over 3 - 6 minutes  
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What are the advantages of continuous thermodilution method over traditional thermodilution method?   respiratory variations are not a factor, eliminates time consuming admin of thermal injectate, reduced chance of inaccuracy since "human error" element taken out of play  
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What are the weaknesses of continuous thermodilution method of cardiac output measurement?   rapid central IV bolus infusions & post bypass pump fluid still decrease accuracy; approximate 10 minute delay can cause acute changes to be inaccurate  
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How does an esophageal doppler work to determine cardiac output?   small probe inserted into esophagus that estimates SV of blood in descending aorta (which is 70% of CO); formulate applied that estimates remaining 30% of CO and adds it to measured total to produce total CO estimation  
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What are the weaknesses of the esophageal doppler method of cardiac output measurement?   dependent upon many assumptions & nomograms which hinder accuracy in a variety of clinical situations; contraindicated in esophageal pathology and coagulopathy  
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Explain the partial CO2 rebreathing method of estimating cardiac output.   ETCO2 reflects pulmonary capillary blood flow; this requires tracheal intubation and mechanical ventilation  
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How is cardiac output calculated via an arterial pressure waveform?   calculates stroke volume from area under waveform; requires a well defined waveform since the dicrotic notch indicates end-systole  
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What are the strengths of arterial pressure waveform cardiac output measurement?   provides a beat to beat cardiac output measurement and its accuracy compares to PAC/Swann thermodilution method  
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What are the weaknesses of arterial pressure waveform cardiac output measurement?   frequent dysrhythmias and tachycardia can result in low SV and can affect accuracy  
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What are 3 methods of calculating cardiac output via the arterial pressure waveform?   LiDCO, PiCCO, and Flo Trac  
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Explain the thoracic bioimpedance method of measuring cardiac output   changes in thoracic volume cause changes in thoracic resistance (bioimpedance) to low amplitude, high frequency currents; 4 sets of electrodes on chest used to measure this  
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What are the weaknesses of the thoracic bioimpedance method of measuring cardiac output?   accuracy affected by electrical interference, incorrect placement of electrodes, previous heart surgery, aortic valve disease, acute changes in sympathetic nervous function (spinal block); can't use in open heart cases  
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