MH Addiction Drug action
Quiz yourself by thinking what should be in
each of the black spaces below before clicking
on it to display the answer.
Help!
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| Michigan's legal limit (breathalyzer)? | 0.08%
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| ___86% liquor. ___Glass of wine. ___Can/bottle beer. ___lbs person | 1 oz. 4--5 oz. 12 oz. 150 lbs
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| Biological Addiction theories. ETOH & CNS Depressants act on ____. | GABA
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| Biological addiction theories. Inactivates ____&___In mice (⬆️ Or ⬇️) cocaine rewards | Serotonin & Dopamine. ⬇️⬇️
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| ETOH & opiates slot into receptors sites in the ___ brain | Mid
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| (__1__) is a normal NT that moderates stress & makes us feel well. ETOH metabolized in (__2__) produces (__3__) which saturates (__1__) receptor sites. This results in (⬆️ Or ⬇️) synthesis & (⬆️ Or ⬇️) of natural (__1__) | 1. Met-enkephalins. 2. Liver. 3. THIQ. ⬇️ & ⬇️
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| (__1__) Causes a craving of ETOH/Opiates. People prone to alcoholism produce (⬆️ Or ⬇️) THIQ in their liver when they drink. | 1. ⬇️⬇️ Met-enkephalins. ⬆️⬆️
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| General depressant withdrawal syndrome. Benzodiazepines. Barbiturates. Alcohol. (_1_) receptors are ⬇️⬇️ Regulated. When (__2__) DEPRESSANT stopped, inadequate (__1__) INHIBITITION ==(__3__) | 1. GABA 2. CNS 3. Withdrawal Symptoms
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| The (__) the half-life of the substance the (__) the withdrawal | Longer. Shorter
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| Activate endorphin receptors causing an increase release of dopamine | Opiates-heroin & OxyCotin
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| Causes the release of dopamine and norepinephrine and blocks the process of de-gradation | Amphetamine
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| Chronic use of amphetamines causes permanent damage to__transportation and production structures. Tolerance begins before blood levels drop significantly | Dopamine
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| Disrupts serotonin pathways. Sometimes permanently | Hallucinogens and dissociative
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| Disrupts glutamate receptor sites and dopamine. | PCP
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| PCP is a? | Hallucinogen
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| Ectasy MDMA 3,4 methylenedioxyamphetamine has | Stimulant and dissociative properties
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| Causes release of serotonin and dopamine. Damages and destroys dopamine serotonin containing neurons | Ectasy
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| ___ Prevents the reuptake of dopamine in the ventral trigeminal Area (__) To the nucleus ACCUMBENS (____) and creates a sensation a pleasure | Cocaine. Brainstem. Limbic system
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| Binds to serotonin and norepinephrine receptors while simultaneously blocking reuptake | Cocaine
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| Chronic use of cocaine result in down regulation of __1__Receptors. During withdrawal (hi or low) __1__ causes the craving | Dopamine. Low Dopamine
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| Marijuana. THC bInds to ___ receptors. THC (⬆️ Or ⬇️ __) release causing decreased activity | Anandamide. ⬇️ Dopamine
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| Paradoxically THC stimulates the ventral trigeminal area (in the___) to the nucleus ACCUMBENS (__) Creating a sense of pleasure | Brain stem. Limbic system
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