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Veterinary Pain/Inflammation

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Question
Answer
NSAID, Aspririn,   ASA  
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NSAID, Phenylbutazone   Butequene  
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NSAID, flunixin   Banamine  
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NSAID, ketoprofen   Anafen  
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NSAID, tofenamic acid   Tolfedine  
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NSAID, meloxicam   Metacam  
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NSAID, carprofen   Rimadyl  
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NSAID, meclofenamic acid   Arquel  
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NSAID, vedaprofen   Quadrisol  
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NSAID, dipyrone   Dipyrone  
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NSAID,acetominophen (not a true NSAID, no anti-inflammatory effects, only analgesic)   Tylenol  
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NSAIDS in general   weak acids, protein bound, absorbed in stomach, additive effect (too much = bad), GIT ulceration (v/d, blood in stool), be careful in liver/kidney disease patients, cats are sensitive and cannot form glucaronic acid (CAUTION in Cats)  
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NSAID Side effects   decrease platelet aggregation, bleeding, GIT ulceration, nephrotoxic in horses and bone marrow suppression in cats, Rimadyl (beware liver effects)  
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DMSO, antiinflammatory   increases absorption of other drugs (vehicle), give topical/IV, freezes at 18 degrees C, wear gloves when using, gives garlic odor and taste when touching, scavenges free radicals  
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Polysulfated glycosaminoglycans   Adequan, very expensive chondroprotective agents, variable efficacy, used in degenerative joint disease  
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Hyaluronic acid   Hyonate, chondroprotective  
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Pentosan polysulfate Na   Cartrophen, chondroprotective  
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Methocarbamol   Robaxin, muscle relaxant, reduce muscle hyperactivity by blocking nerves in the spinal cord  
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Corticosteroids in general   pruritis, dermatitis, arthritis, sprains, muscle soreness, rheumatoid arthritis, allergies, cancer  
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Corticosteroids SE   Pu/Pd, decreased healing rate, polyphagia, weight gain, abnormal behavior, panting, increased activity, GIT bleeds, iatrogenic cushings, laminitis  
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Corticosteroids CI   Acute and chronic bacterial infections, CHF, diabetes, chronic nephritis, pregnancy (abortions)  
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Hydrocortisone   Forte-Topical, short acting  
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Cortisone   Short acting  
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Prednisone   Predsone5, intermediate acting  
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Prednisolone   Vanectyl-P, Intermediate acting  
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Methylprednisolone   Intermediate acting  
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Triameinolone   Panalog, intermediate acting  
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Dexamethasone   Long acting  
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Betamethasone   Long acting  
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Flumethasone   Long acting  
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Corticosteroid uses   Inflammatory = low dose, immunosuppressive = moderate dose, shock = high dose  
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Opioids general   block receptors in brain, spinal cord and peripheral tissues, antitussive, respiratory depressants, increase IOP, vomiting, defecation, miosis (dogs), mydrasis (cats), bradycardia, panting, excitement, histamine release  
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Opioids SE   constipation, respiratory depression, sedation, excitement (cats and horses), MUST KEEP METICULOUS RECORDS  
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Morphine   Infumorph  
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Meperidine   Opioid  
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Hydromorphone   Diluadid  
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Fentanyl   Dergesic  
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Butorphanol   Torbugesic, Torbutrol  
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Antihistamines general   Block H1 receptors, SE= drowsy, excitable (cats and horses), weakness, dry MM, reduce motion sickness (H1 receptors in inner ear)  
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Diphenhydramine   Benadryl, CI= bladder obstruction, don't use with other drugs, AE = drowsy, dizzy, nausea, dry mouth, avoid SQ, anxiety  
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Dimenhydrinate   Gravol, CI= glaucoma, chronic lung disease, AE= drowsy, dry mouth, nausea, CNS depression  
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Terfenadine   Apoterfenidine, don't use with anti-fungals  
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Chlorpheniramine   Cortabs, dermatitis  
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Prednisolone trimeprazine tartrate   Vanectyl-P, antipruritic, dermatitis  
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