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Pharmacology
Veterinary Pain/Inflammation
| Question | Answer |
|---|---|
| NSAID, Aspririn, | ASA |
| NSAID, Phenylbutazone | Butequene |
| NSAID, flunixin | Banamine |
| NSAID, ketoprofen | Anafen |
| NSAID, tofenamic acid | Tolfedine |
| NSAID, meloxicam | Metacam |
| NSAID, carprofen | Rimadyl |
| NSAID, meclofenamic acid | Arquel |
| NSAID, vedaprofen | Quadrisol |
| NSAID, dipyrone | Dipyrone |
| NSAID,acetominophen (not a true NSAID, no anti-inflammatory effects, only analgesic) | Tylenol |
| NSAIDS in general | weak acids, protein bound, absorbed in stomach, additive effect (too much = bad), GIT ulceration (v/d, blood in stool), be careful in liver/kidney disease patients, cats are sensitive and cannot form glucaronic acid (CAUTION in Cats) |
| NSAID Side effects | decrease platelet aggregation, bleeding, GIT ulceration, nephrotoxic in horses and bone marrow suppression in cats, Rimadyl (beware liver effects) |
| DMSO, antiinflammatory | increases absorption of other drugs (vehicle), give topical/IV, freezes at 18 degrees C, wear gloves when using, gives garlic odor and taste when touching, scavenges free radicals |
| Polysulfated glycosaminoglycans | Adequan, very expensive chondroprotective agents, variable efficacy, used in degenerative joint disease |
| Hyaluronic acid | Hyonate, chondroprotective |
| Pentosan polysulfate Na | Cartrophen, chondroprotective |
| Methocarbamol | Robaxin, muscle relaxant, reduce muscle hyperactivity by blocking nerves in the spinal cord |
| Corticosteroids in general | pruritis, dermatitis, arthritis, sprains, muscle soreness, rheumatoid arthritis, allergies, cancer |
| Corticosteroids SE | Pu/Pd, decreased healing rate, polyphagia, weight gain, abnormal behavior, panting, increased activity, GIT bleeds, iatrogenic cushings, laminitis |
| Corticosteroids CI | Acute and chronic bacterial infections, CHF, diabetes, chronic nephritis, pregnancy (abortions) |
| Hydrocortisone | Forte-Topical, short acting |
| Cortisone | Short acting |
| Prednisone | Predsone5, intermediate acting |
| Prednisolone | Vanectyl-P, Intermediate acting |
| Methylprednisolone | Intermediate acting |
| Triameinolone | Panalog, intermediate acting |
| Dexamethasone | Long acting |
| Betamethasone | Long acting |
| Flumethasone | Long acting |
| Corticosteroid uses | Inflammatory = low dose, immunosuppressive = moderate dose, shock = high dose |
| Opioids general | block receptors in brain, spinal cord and peripheral tissues, antitussive, respiratory depressants, increase IOP, vomiting, defecation, miosis (dogs), mydrasis (cats), bradycardia, panting, excitement, histamine release |
| Opioids SE | constipation, respiratory depression, sedation, excitement (cats and horses), MUST KEEP METICULOUS RECORDS |
| Morphine | Infumorph |
| Meperidine | Opioid |
| Hydromorphone | Diluadid |
| Fentanyl | Dergesic |
| Butorphanol | Torbugesic, Torbutrol |
| Antihistamines general | Block H1 receptors, SE= drowsy, excitable (cats and horses), weakness, dry MM, reduce motion sickness (H1 receptors in inner ear) |
| Diphenhydramine | Benadryl, CI= bladder obstruction, don't use with other drugs, AE = drowsy, dizzy, nausea, dry mouth, avoid SQ, anxiety |
| Dimenhydrinate | Gravol, CI= glaucoma, chronic lung disease, AE= drowsy, dry mouth, nausea, CNS depression |
| Terfenadine | Apoterfenidine, don't use with anti-fungals |
| Chlorpheniramine | Cortabs, dermatitis |
| Prednisolone trimeprazine tartrate | Vanectyl-P, antipruritic, dermatitis |
Created by:
jtwilks
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