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MH Pharm & Treatment

Quiz yourself by thinking what should be in each of the black spaces below before clicking on it to display the answer.
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Question
Answer
Potency   the amount of the drug needed to achieve that maximum effect Low Potency requires Higher Dosage to achieve efficacy   show
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Efficacy   show  
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Half life   show  
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show use of a drug that for a condition that differs from the one involved in the original FDA testing    
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show serious life threatening side effects that are located on a insert highlighted, boxed and located separate from the other text.    
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Principals of Psychotropic Drugs   1.Identify Target Symptoms 2.Allow for Sufficient time on medication before evaluation 3.Use the lowest effective dose 4.Use the lowest dose for older adults   show
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What are Anti psychotic drugs?(dopamine blockers)   show  
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show NO!    
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What are typical, conventional, anti psychotics?   show  
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Two categories of typical anti psychotics   Phenothiazines ~chlorpromazine (Thorazine) ~prochlorperazine (Compazine) ~fluphenazine hydrochloride (Prolixin)   show
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What warning should be taken with elderly patients and atypical anti psychotics?   show  
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show Extrapyramidal Syndrome EPS    
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What are the 4 conditions of EPS?   pseudoparkinsonism, Acute Dystonia, Akanthisia, and Tardive dyskinesia   show
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show Tremors, Masklike face, Rigidity, Shuffling gait Treated by changing antipsychotic medication therapy, change the antipsychotic drug, adding an anticholinergic , or amantadine    
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Signs and Symptoms of Acute Dystonia   show  
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Signs and symptoms of Akathisia   Restlessness Constant moving treated by a change in anti psychotic medication or by adding a beta-blocker, anticholinergic or benzodiazepine   show
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Signs and symptoms of Tardive dyskinesia   show  
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show Cogentin (benztropine) most common Symmetrel (amantadine)    
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show Are more commonly used have fewer side effects and use dopamine and serotonin transmitters   EX. clozapine (Clozaril) risperidone (Risperadal) olanzapine (Zyprexa) ziprasidone (Geodon)  
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Common side effects of all antipsychotic medications?   Anticholinergic effects (dry out) Hypotension/hypertension, blood dyscrasis (Clozaril), photosensitivity, weight gain*, tachycardia, high cholesterol HDL 40 for women and 50 for men 150mg/dL triglycerides. Increase blood sugar levels   show
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What side effect is special to Clozaril   show  
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show 1. Monitoring- constantly check patients Vitals. Look for hypotension and tachycardia. 2. Look for EPS and NMS signs and symptoms. 3. Check Labs. Check glucose and WBC along with baseline lab work. BUN and Live enzymes   5. Make sure the patient protects themselves from sun exposure 6. Teach patient to avoid alcohol consumption 7. Do not stop taking medications 8. Take missed dose with in 3-4 hrs and medication can take 3-6 weeks to work  
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What is NMS?   show  
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show *FEVER OVER 104 F* Difficulty Breathing Tachycardia, irregular pulse, unstable bp, diaphoresis, altered LOC, elevated WBC.    
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show * Notify Physician* Discontinue medications Monitor Vitals, LOC, and Electrolytes Take seizure precautions   Administer Antipyretics Utilize Cooling blanket  
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Client teaching for Anticholinergic effects   exercising and drinking plenty of water and bulk forming food in the diet. Also use stool softeners and avoid laxatives.   show
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show use to treat depressive illness, anxiety disorders, and depressed phase of bipolar disorder    
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show 1.Tricyclic and cyclic depressants 2.SSRI 3.MAOI 4. Others    
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SSRI Selective Serotonin Reuptake Inhibitors   show Ex. Fluoxetine Hydrochloride (Prozac) Sertraline Hydrochloride (Zoloft) Paroxetine (Paxil) Citaloprim (Cylexa)  
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show N/V and diarrhea CNS stimulation -agitation, pacing Akathisia, Dry mouth photosensitivity Insomnia, Dizziness, weight gain, sexual dsyfunction    
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What two side effects are special to SSRI's?   Insomnia CNS stimualtion   show
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Can you take a SSRI and a MAOI together? Why or why not?   show  
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Nursing Actions, Care, and Techniques for SSRI   Monitor: Vitals, Weight, Labs and Suicidal patients Must have a base line set of vitals Zoloft no grape fruit   show
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When can I take a missed dose of SSRI medication?   With in 8 hours of missed dose   show
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How long does it take for SSRI to take on full therapeutic effect   2-3 weeks   show
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show SSRI because of the length of time to take therapeutic effect    
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What are the side effects of Serotonin Syndrome?   Aggitation, diaphoresis, fever, tachycardia,hyper reflexia   show
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show Tricyclic Antidepressants oldest category of antidepressants more extreme side effects can be deadly and cardiotoxic    
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show Seizure threshold Anti hypertensive therapy interactions Interaction with alcohol Interaction with MAOI    
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Examples of TCA?   Clomipramine hydrochloride (Anafranil) Amitriptyline Hydrochloride (Elavil) Mirtazapine (Remeron)   show
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show Anticholinergic Effects Photosensitivity Cardio Disturbances Orthostatic disturbances Sedation Anxiety Weight gain Decreased/ Increased Libidi    
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Which side effects are special to TCA's   Thrombocytopenia Cardiac Disturbances, (Arrythmia MI and Strokes) Anticholinergic effects Seizures   show
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Nursing Actions for TCA   show Change positions slowly, Take medication at night Avoid Alcohol  
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How long before TCA reaches therapeutic effectiveness?   4 to 6 weeks   show
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When can a patient take a missed dose of a TCA?   show  
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What is a MAOI?   Monoamine Oxidase Inhibitors Oldest Category , Most potent Last effort   show
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Examples of MAOI   Phenelxine sulfate (Nardil) Tranylcypromine (Parnate)   show
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What type of patients should not use MAOI?   Cardiac, BP, and Asthma patients   show
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show Do not eat food with tyramine because it can cause the patient to go into a life threatening hypertensive crisis    
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Which foods should the nurse include in patient teaching to a patient on MAOI's   show Tap beers Yogurt, sour cream, peanuts , brewers yeast  
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Side effects of a MAOI   Daytime sedation and lethargy GI Upset Weight gain Insomnia Sexual dysfunction dizziness orthostatic hypotension   show
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Which side effect is special to MAOI   Hypertensive Crisis   show
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Nursing Actions for MAOI   Monitor Vitals Compliance- Are they taking their medications? Dosing Considerations - side effects are specific to patient Change positions slowly   show
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show Medications used to help decrease manic swings associated with bipolar disorders. Helps minimize the kindling process.    
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What is the example of a mood stabilizer?   show  
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What chemical is Lithium dependent upon?   show  
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What is the therapeutic range of Lithium?   show  
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Side effects of Mood Stabilizers   Polyuria polydypsia Anorexia Nausea Dry mouth   show
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show Alopecia, Fine hand tremors (increase with toxicity), and lethargy    
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How often does Lithium levels need checking?   show  
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Nursing Actions for Lithium...   Monitor Lithium levels Watch for suicide risk- lethal OD Advise patient to take with food and to drink 6-8 glasses of water Lithium must be tapered   show
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How long does it take Lithium to reach level of therapeutic response?   show  
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show Prolonged polyuria, polydypsia, and vomiting    
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show when serum levels are above 1.5 mEq/L    
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What happens during Mild Lithium Toxicity?   Serum levels are 1.5 - 2.0 mEq/L Patient experiences: Apathy, Lethargy, Diminished concentration, mild ataxia/muscle weakness (difficulty walking), and coarse hand tremors   show
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What happens during Moderate Lithium Toxicity?   Serum levels 2.0-2.5 mEq/L Patient experiences N/V, severe diarrhea, mild to moderate ataxia and incoordination (not walking), slurred speech, tinnitus, blurred vision, and irregular tremors   show
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show Serum levels above 2.5 mEq/L Patient experiences Nystagmus (twitching of the eyes), muscle fasciculation(muscles move on their own), hyperreflexia, visual and tactile hallucinations, oliguria and anuria, impaired LOC, and grand mal seizures, coma, &death    
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show 1.Hold Lithium dose 2.Call DR 3. Monitor Vitals,& LOC 4. Cardiac Status - Telemetry EKG 5.LABS- BUN, Kreatin, Liver enzyme, and Metabolic Panel 6.Seizure precautions 7. Suicide precautions until OD can be ruled out.    
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What is the intended use for Anti anxiety medications/ anxiolytics ?   show  
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Name three examples of anti anxiety medications?   show  
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What are the side effects of anti anxiety medications?   show  
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What are the S/S of over dose/ toxicity of anti anxiety medications?   show  
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show Flumazenil (Romazicon)    
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Nursing Actions for anti anxiety drug?   Monitor - motor responses, autonomic responses, paradoxical responses, and visual disturbances, and Labs   show
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show ~inform patient that anti anxiety medication are aimed to relieve symptoms of anxiety and insomnia but do not treat the underlying cause. ~Benzodiazepines enhances the effects of alcohol ~Slows reaction time and should not drive until become use to med   ~with drawl can be fatal do not stop medications abruptly  
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show ~mostly used to ADHD children and adolescents, residual ADD in adults, and narcolepsy.    
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show Anorexia Weight loss Nausea Growth and weight suppression Dry mouth irritability    
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What are 3 examples of Stimulants?   Methylphenidate (Ritalin) Amphetamine (Adderall) Atomoxetine (Strattera)   show
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Dosage consideration for Stimulants   Dosage for children with ADHD are based on age, weight, and behavior of the child the child , along with the family tolerance for the child's behavior.   show
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What is the client teaching for sitmulants?   Inform patient about the potential for abuse. Take medication after meals 10 day supply can be fatal keep out of reach of children Avoid Caffeine   show
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show Is used with alcoholics who are motivated to refrain from drinking.    
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What is the Mechanism of Action of Disulfiram?   show  
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Signs and symptoms of Disulfiram   Vasodilation, Headache, sweating, dry mouth, nausea, vomitting, dizziness, and weakness. holitosis, impotence, tachycardia   show
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Nursing actions and teachings for Disulfiram   Never give Disulfiram to patients under the influence of alcohol without informing patient and or family of the side effects. Teach patients to look out for every day products that contain alcohol   show
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What classification of Carbamazepine (Tegretol)?   show  
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What classification of Methylphenidate (Ritalin)?   Stimulant   show
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What classification of Benztropine (Cogentin) ?   show  
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What classification of Amitriptyline (Elavil) ?   Tricyclic antidepressant   show
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show SSRI antipsychotic    
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show Atypical antipsychotic    
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What classification of Clonazepam (Klonopin)?   Benzodiazepine   show
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What classification of Quetiapine (Seroquel)?   Atypical antipsychotic   show
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What are the sign/ symptoms of Serotonin syndrome   Hypothermia Autonomic instability/ delirium Rigidity Myoclomus   show
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What are the characteristic of anticholinergic side effects.   show  
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More side effects of antipsychotic drugs   Impotence Sedation/ seizures Hypotension Akanthisia Dermatological side effects EPS   show
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show Anti psychotics, antidepressants, mood stabilizers, anxiolytics, and stimulants    
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