Microbiology: Microbial Interaction with Humans
Quiz yourself by thinking what should be in
each of the black spaces below before clicking
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show | Parasite
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show | collection of microbes normally found within a healthy body
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show | Disease causing parasite
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show | Causes disease in the absence of normal host resistance
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Pathogenicity | show 🗑
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What is the quantitative measurement of an organisms ability to cause disease? | show 🗑
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Our body is not uniform describes the differences in | show 🗑
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Epithelial cells have ___ to help wash away microorganisms | show 🗑
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Where can microbes grow on the outer surfaces | show 🗑
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show | dry and acidic
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show | Main sweat glands that are responsible for thermoregulation
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show | Wherever there is hair
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show | Organisms that don't grow but are contaminants
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show | Able to grow on skin, most G+
Examples: Staphylococcus, corynebacteria, and P. acne
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show | Breaks glycosidic linkages in peptidoglycan
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Mouth Protection: Lactoperoxidase | show 🗑
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show | Streptococci and Lactobacilli, when teeth grow in we get colonies
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show | Thick layer of bacteria and polymers that they secrete
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Steps in plaque growth | show 🗑
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What are the facultative bacteria of the teeth? | show 🗑
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show | Fusobacteria and actinomyses
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show | Streptococcus mutans and Streptococcus sobrinus
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S. mutans | show 🗑
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show | Dextransucrase
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Helicobacter pylori | show 🗑
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show | Nearest the stomach, fairly acidic, similar flora of stomach
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show | pH is more alkaline and more bacteria; Enterococci and Lactobacilli
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show | E. coli and Enterococcus faecalis
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Large Intestine Obligative Anaerobes | show 🗑
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show | Gas and odor products
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What are produced in the large intestine? | show 🗑
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Streptococcus pyogenes | show 🗑
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show | Staph infections and boils
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Corynebacterium diptheriae | show 🗑
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show | pneumonia
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Smoker's cough | show 🗑
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Lactobacillus scidophilus | show 🗑
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Onset of puberty in vagina causes secretions of | show 🗑
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Tissue specificity | show 🗑
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Host Specificity | show 🗑
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show | Glycocalix (polysaccharides on cell surface) and fimbriae (binds to glycoproteins on cell surface- mannose)
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show | fimbriae-like proteins that allow organism (E. coli) to attach to the mucosa of the small intestine
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show | Have CFA's and toxins that produce diarrhea. Large intestine.
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Transferrin and Lactoferrin | show 🗑
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show | Iron or ferrin (Fe) binding proteins
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Aerobactin | show 🗑
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show | pathogens grow locally and do not spread out
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show | Extensive growth in tissue happens some of he organisms can overflow into the blood
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show | or systemic infection; continued growth and infection in the blood.
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show | toxicity and invasiveness
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Clostridium tetani | show 🗑
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show | Highly invasive and multiplies rapidly in lung tissue
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LD50 | show 🗑
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show | Infectious dose to infect 50% of population
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show | Any extracellular proteins that are produced by pathogen and is essential for disease causing
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show | Combines toxins, invasiveness and virulence factors to be more pathogenic
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show | Substance having a specific toxic effect on certain cells
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show | a cytotoxin specific for cells of intestinal mucosa
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Endotoxin | show 🗑
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Attenuation | show 🗑
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Hyaluronidase | show 🗑
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Collagenase | show 🗑
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Streptokinase | show 🗑
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show | Promotes fibrin clotting and stops defense from reaching cells
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Hemolysis | show 🗑
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show | Lyse WBC and decrease host resistance
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Exotoxins | show 🗑
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Diphtheria toxin | show 🗑
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show | Unless incorporated into gene C. diptheriae does not produce the toxin
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Tetanus toxin is produced by | show 🗑
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Botulinum Toxin | show 🗑
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show | Form of exotoxins in small intestine and cause massive secretion of fluid into intestine
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Food poisoning bacteria | show 🗑
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show | Vibrio cholerae, enteropathogenic E. coli, and Salmonella enteritidis
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show | Diarrheal disease by cholera enterotoxin (Vibrio cholereae, G-, comma shaped)
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Endotoxins | show 🗑
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Limulus assay | show 🗑
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Specific host defenses | show 🗑
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show | against all pathogens
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Tissue Specificity | show 🗑
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