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Chapter 8

Quiz yourself by thinking what should be in each of the black spaces below before clicking on it to display the answer.
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Question
Answer
what are some of the viruses known to be linked to cancer   liver inf/hep/ebvirus/herpes/hpv  
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cytoxic defined   chemicals that are toxic to cells, preventing their reproduction or growth  
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antineoplastic defined   drug intended to inhibit or prevent the maturation and proliferation of neoplasms that may become malignant  
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cycle-phase-nonspecific agents defined   agents that work on a cell at any time during the cells cycle  
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5 types of cycle-phase-nonspecific agents   *nitrogen mustard*ethylenimines*alkyl sulfonates*triazenes*nitrosources  
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cycle-phase-specific agents defined   agents work on a specific cycle during the cell cycle.used for rapid growing tumors  
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name 5 types cycle-phase-specific agents   *carboplatin*cisplatin*ifosfamide*paclitaxel*mesna  
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mutagenic defined   causes cells to mutate  
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carcinogenic defined   causes cancer  
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teratogenic   can cause birth defects  
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BSC   biological safety cabinet  
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what class BSC should chemo agents be prepared in   class II  
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what are the 2 main differences of a BSC   *some are directly vented outside *others filter the air againbefore recirculatin  
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BSC are validated every ____mos for integrity   6  
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HEPA filters are recertified every _____________mos   6/or if hood is removed  
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shadowing defined   the act of blocking air flow in the BSC  
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properly trained employees should have these requisites/knowledge when working with aseptic procedures(4)________,_________,___________,_________   *proper training*compentency assessment*cont ed*recertification yrly  
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teratogenic defined   tending to produce anomalies of formation  
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aerosolization defined   suspension of small particles(liq or powder) in the air  
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define permeability   property or state of being penetrable  
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what are some of the risks assoc w/the handling of chemo drugs(2)_____________________,____________________   *drug may get out of the container and in the air  
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the drug may enter the handlers body thru (5)   inhalation,aborbtion,ingestion,accidental injection  
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