1.8
Quiz yourself by thinking what should be in
each of the black spaces below before clicking
on it to display the answer.
Help!
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| Naloxone (Narcan) | Non-selective opioid antagonist
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| What do nociceptors cause? | Na+/Ca2+ influx
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| Allodynia | Normal stimulus is perceived as pain
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| Hyperalgesia | Normal pain is perceived as worse
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| How do opioids decrease neurotransmittors? | Binds to G protein which blocks Ca2+ channels, preventing neurotransmission cascade
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| What are three contraindications for opioid use? | Asthma, hepatic disease, renal disease
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| Meperidine (Demerol) | Short-acting 5-HT blocker
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| Methadone (Dolophine) | NMDA antagonist; used in opioid dependence
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| Buprenorphine (Buprenex) | Partial mu agonist; kappa antagonist; used in opioid dependence
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| Nalorphine (Lethidrone) | Partial opioid antagonist
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| Tramadol (Ultram) | Weak mu agonist; NE and 5-HT blocker
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| Tapentadol (Nucynta) | Potent mu agonist; NE blocker
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| Pentazocine (Talwin) | Kappa agonist; weak mu agonist
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| What is balanced anesthesia? | IV + inhalation mask
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| Thiopental Sodium (Pentothal) | Short-acting barb; increase GABA-A opening duration
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| Midazolam (Versed) | Benzo; increase GABA-A opening
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| Ketamine (Ketelar) | Dissociative anesthetic; NMDA antagonist
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| Fentanyl (Sublimaze) | Opioid; mu receptor agonist
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| Etomidate (Amidate) | Benzo-like; increase GABA-A opening
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| Propofol (Diprivan) | Benzo-like; increase GABA-A opening
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| Droperidol (Inapsine) | D2 antagonist; H1 antagonist
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| Donepezil (Aricept) | Cholinesterase inhibitor (Alzheimer's)
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| Rivastigmine (Exelon) | Cholinesterase inhibitor (Alzheimer's)
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| Galantamine (Razadyne) | Cholinesterase inhibitor (Alzheimer's)
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| Memantine (Namenda) | NMDA antagonist
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| The Frank-Starling Law states: | Cardiac output increases with increased preload
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| Myositis | Myalgia with elevated creatine kinase
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| Zetia (Ezetimibe) | Decreases dietary cholesterol via inhibition of NPC1
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| Atorvastatin (Lipitor) | HMG-CoA reductatse inhibitor
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| Cholestyramine (Questran) | Bile Acid Sequestrant: inhibits enterohepatic recirculation of bile
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| Fenofibrate (Tricor) | PPARa activator
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| Gemfibrozil (Lopid) | PPARa activator
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| PPARa activators | Increase Beta-oxidation of FFA
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| Niacin (nicotinic acid) | Adverse flushing reaction
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| Colesevelam (Welchol) | Bile Acid Sequestrant: inhibits enterohepatic recirculation of bile
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| Simvastatin (Zocor) | HMG-CoA reductase inhibitor
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| Pravastatin (Pravachol) | HMG-CoA reductase inhibitor
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| Clofibrate (Atromid) | PPARa activator
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sdeck86
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